RT Journal Article SR Electronic T1 Induced Hypothermia as a Neuroprotectant in Post-Cardiac Arrest JF Ochsner Journal JO Ochsner J FD O. P. Jindal Global University SP 278 OP 281 VO 9 IS 4 A1 Mohi E. Alkadri A1 Paul McMullan YR 2009 UL http://www.ochsnerjournal.org/content/9/4/278.abstract AB Survivors of out-of-hospital cardiac arrest frequently suffer devastating effects from anoxic brain injury. Therapeutic hypothermia is the first therapy to show benefit in improving survival as well as limiting neurologic injury. We review the data supporting the use of therapeutic hypothermia in this patient population, the pathophysiologic basis of its neuroprotectant effects, the methods of hypothermic induction, and the clinical application.