RT Journal Article
SR Electronic
T1 Steroids: Pharmacology, Complications, and Practice Delivery Issues
JF Ochsner Journal
JO Ochsner J
FD O. P. Jindal Global University
SP 203
OP 207
VO 14
IS 2
A1 William Ericson-Neilsen
A1 Alan David Kaye
YR 2014
UL http://www.ochsnerjournal.org/content/14/2/203.abstract
AB Background Since their identification nearly 80 years ago, steroids have played a prominent role in the treatment of many disease states. Many of the clinical roles of steroids are related to their potent antiinflammatory and immune-modulating properties.Methods This review summarizes the basic pharmacology, complications, and practice delivery issues regarding steroids.Results Clinically relevant side effects of steroids are common and problematic. Side effects can occur at a wide range of doses and vary depending on the route of administration. The full spectrum of side effects can be present even in patients taking low doses.Conclusions Practitioners must be aware that these drugs might exacerbate a preexisting condition or present a new medical condition. Knowledge of the clinical implications of prescribing these agents is critical.