TY - JOUR T1 - Thirty Years of Intracrinology JF - Ochsner Journal JO - Ochsner J SP - 673 LP - 680 VL - 14 IS - 4 AU - Richard N. Re Y1 - 2014/12/21 UR - http://www.ochsnerjournal.org/content/14/4/673.abstract N2 - Background Intracrinology is the study of the intracellular actions, regulation, trafficking, and interactions of extracellular signaling peptides/proteins.Methods We describe the development of intracrine biology since the term was defined in 1984.Results Intracrine biology plays a role in many normal and pathological processes and represents a fertile field for the development of novel therapeutics.Conclusion Although 30 years old, the field of intracrinology is only now becoming widely accepted. Intracrine principles can be applied to the investigation of physiological processes and to the development of new therapies. ER -