RT Journal Article SR Electronic T1 Septic Embolic Stroke Resulting From Staphylococcus lugdunensis Endocarditis JF Ochsner Journal JO Ochsner J FD O. P. Jindal Global University SP 184 OP 188 VO 17 IS 2 A1 Htoo Kyaw A1 Atif Z. Shaikh A1 Gokul Yaratha A1 Misra Deepika YR 2017 UL http://www.ochsnerjournal.org/content/17/2/184.abstract AB Background: Staphylococcus lugdunensis, a member of the coagulase-negative staphylococci (CoNS), has been recognized as a causal organism for infective endocarditis since the 1980s. Although most CoNS have an insidious and chronic nature, they are involved in a variety of systemic infections. S lugdunensis infective endocarditis is a rare entity but is as catastrophic as Staphylococcus aureus infective endocarditis and requires aggressive antibiotic therapy and, typically, valve replacement. S lugdunensis infective endocarditis–induced septic embolic cerebrovascular accident has rarely been reported in the literature.Case Report: We present the case of a 63-year-old African American man who presented with sudden-onset aphasia and right-sided hemiplegia and was admitted for the management of cerebrovascular accident. Afterwards, he developed a fever and was found to have S lugdunensis bacteremia, with subsequent imaging revealing vegetations of the mitral valve. Despite being treated with culture-appropriate antibiotics, he remained persistently bacteremic and required surgical mitral valve replacement.Conclusion: S lugdunensis infective endocarditis is rare but can have a malignant course and requires early surgical intervention in most cases.