RT Journal Article SR Electronic T1 Primary Undifferentiated Pleomorphic Sarcoma of the Penis JF Ochsner Journal JO Ochsner J FD O. P. Jindal Global University SP 434 OP 437 VO 17 IS 4 A1 Hyung Sun Yoo A1 Suma Satti A1 Marc Matrana YR 2017 UL http://www.ochsnerjournal.org/content/17/4/434.abstract AB Background: Primary penile sarcoma is a rare disease that affects men of all ages. Different subtypes of primary penile sarcoma exist, with the rarest being pleomorphic sarcoma. Delays in presentation and diagnosis of primary penile sarcoma have been reported because of its benign-appearing presenting features and rarity. If penile sarcoma is left untreated, the clinical consequence is metastasis that is fatal in most cases.Case Report: We report an extremely rare case of undifferentiated pleomorphic sarcoma of the penis in a 59-year-old patient who initially presented with a slow-growing penile nodule. The tumor was surgically excised, but the patient experienced local recurrence and, despite receiving chemotherapy and surgery, died of metastatic disease 15 months after initial presentation.Conclusion: Vigilance regarding biopsy and intervention for penile nodules may lead to early diagnosis and improved clinical outcomes.