@article {Ayoub456, author = {Peter J. Ayoub and Angela Parise}, title = {Intravaginal Application of Topical Black Salve for High-Grade Cervical Intraepithelial Neoplasia}, volume = {20}, number = {4}, pages = {456--458}, year = {2020}, doi = {10.31486/toj.19.0044}, publisher = {Ochsner Journal}, abstract = {Background: Black salve, or sanguinarine, is a topical escharotic agent that has been used by patients for homeopathic ablation of epithelial dysplasia, including cervical intraepithelial neoplasia.Case Report: A 33-year-old female presented to the obstetric and gynecologic clinic for management of a missed abortion. At the time of presentation, she admitted to the use of topical black salve for treatment of cervical intraepithelial neoplasia 2 years prior. Speculum examination revealed a stenotic cervix that appeared flush against the vaginal cuff. Hysteroscopy performed 4 months later after the patient developed new oligomenorrhea revealed significant vaginal scarring with formation of a blind pouch that concealed the true cervix.Conclusion: Health care providers should be aware of homeopathic remedies trialed by patients on their own or as an alternative to recommended treatment. Such self-treatment may cause significant patient harm, such as scarring or deformity.}, issn = {1524-5012}, URL = {https://www.ochsnerjournal.org/content/20/4/456}, eprint = {https://www.ochsnerjournal.org/content/20/4/456.full.pdf}, journal = {Ochsner Journal} }