RT Journal Article SR Electronic T1 Intravaginal Application of Topical Black Salve for High-Grade Cervical Intraepithelial Neoplasia JF Ochsner Journal JO Ochsner J FD O. P. Jindal Global University SP 456 OP 458 DO 10.31486/toj.19.0044 VO 20 IS 4 A1 Peter J. Ayoub A1 Angela Parise YR 2020 UL http://www.ochsnerjournal.org/content/20/4/456.abstract AB Background: Black salve, or sanguinarine, is a topical escharotic agent that has been used by patients for homeopathic ablation of epithelial dysplasia, including cervical intraepithelial neoplasia.Case Report: A 33-year-old female presented to the obstetric and gynecologic clinic for management of a missed abortion. At the time of presentation, she admitted to the use of topical black salve for treatment of cervical intraepithelial neoplasia 2 years prior. Speculum examination revealed a stenotic cervix that appeared flush against the vaginal cuff. Hysteroscopy performed 4 months later after the patient developed new oligomenorrhea revealed significant vaginal scarring with formation of a blind pouch that concealed the true cervix.Conclusion: Health care providers should be aware of homeopathic remedies trialed by patients on their own or as an alternative to recommended treatment. Such self-treatment may cause significant patient harm, such as scarring or deformity.