Table 1.

Classification and Percent Distribution of Pineal Region Masses in Six Case Seriesa

World Health Organization Tumor Classification6Edwards et al,16 1988 Ages < 18 years n=36Regis et al,15 1996 Ages 3-73 years n=370Grimoldi et al,18 1998 Ages 9-52 years n=13Hernesniemi et al,19 2008 Ages 0-78 yearsb n=101Abecassis et al,20 2017 Ages 0-66 years n=51Abbassy et al,21 2018 Ages 1-27 years n=11
Germ cell tumors/Germinomas63% / 30%34% / 27%39% / 31%13% / 11%38% / 30%36% / 18%
Pineal parenchymal cell tumors12%24%39%32%26%27%
Glial cell tumors22%34%8%26%14%36%
Miscellaneous tumors and cysts6%12%15%30%22%0%
  • aThe papillary tumor of the pineal region classification is not included in this table, as this entity was not defined until 2003 after 3 of the case series were published. We have classified ependymomas and atypical teratoid rhabdoid tumors as glial tumors and papillary tumors of the pineal region as miscellaneous tumors and cysts.

  • bThis series includes 12 vascular lesions that are not included in the table.