Calculation of the Pulmonary Embolism Severity Index (PESI) and Simplified Pulmonary Embolism Severity Index (sPESI) Scores8,9
| Parameter | PESI Points | sPESI Points |
|---|---|---|
| Age | Age in years | +1, if age >80 years |
| History of cancer | +30 | +1 |
| History of heart failure | +10 | +1 |
| History of chronic lung disease | +10 | +1 |
| Heart rate ≥110 bpm | +20 | +1 |
| Systolic blood pressure <100 mmHg | +30 | +1 |
| Respiratory rate ≥30 breaths per minute | +20 | – |
| Temperature <36°C/96.8°F | +20 | – |
| Altered mental status | +60 | – |
| Oxygen saturation <90% | +20 | +1 |
| Risk Stratification | ||
| PESI Score Total Points | Class | 30-Day Mortality Risk |
| 0-65 | I | 0.0%-1.6% |
| 66-85 | II | 1.7%-3.5% |
| 86-105 | III | 3.2%-7.1% |
| 106-125 | IV | 4.0%-11.4% |
| >125 | V | 10%-24.5% |
| sPESI Score Total Points | 30-Day Mortality Risk | |
| 0 | 1.0% | |
| ≥1 | 10.9% | |
Note: Patients with low scores (PESI ≤85 and sPESI 0) may be treated as an outpatient basis, whereas patients with high scores (PESI >86 and sPESI >1) require escalation of care and immediate intervention.