Patient's Laboratory Data Before and After Vaccination
| Parameter | Reference Range | 4 Days Before First Dose of Vaccine | 2 Weeks After Second Dose of Vaccine | 3 Weeks After Second Dose of Vaccinea |
|---|---|---|---|---|
| Clinical chemistry | ||||
| Sodium, mmol/L | 136–145 | 138 | 140 | |
| Potassium, mmol/L | 3.5–5.1 | 4.4 | 4.2 | |
| Chloride, mmol/L | 95–110 | 104 | 103 | |
| Bicarbonate, mmol/L | 23–29 | 26 | 27 | |
| Anion gap, mmol/L | 5–15 | 8 | 10 | |
| Blood urea nitrogen, mg/dL | 6–20 | 15 | 11 | |
| Creatinine, mg/dL | 0.5–1.4 | 0.9 | 0.9 | |
| eGFR, mL/min/1.73 m2 | >60 | >60 | >60 | |
| Calcium, mg/dL | 8.7–10.5 | 9.3 | 9.8 | |
| Glucose, mg/dL | 70–110 | 107 | 103 | |
| Alkaline phosphatase, U/L | 55–135 | 149 | 135 | |
| Protein total, g/dL | 6.0–8.4 | 7.5 | 8.3 | |
| Albumin, g/dL | 3.5–5.2 | 3.8 | 3.4 | |
| Bilirubin total, mg/dL | 0.1–1.0 | 0.4 | 0.7 | |
| Aspartate transaminase, U/L | 10–40 | 22 | 13 | |
| Alanine transaminase, U/L | 10–44 | 28 | 25 | |
| C-reactive protein, mg/L | 0.0–8.2 | 100 | ||
| Erythrocyte sedimentation rate, mm/h | 0–10 | 92 | ||
| Complete blood count | ||||
| Hemoglobin, g/dL | 14.0–18.0 | 14.3 | 13.3 | |
| Platelets, K/uL | 150–350 | 339 | 407 | |
| White cell count, K/uL | 3.90–12.70 | 9.4 | 9.2 | |
| Neutrophils, % | 38.0–73.0 | 69.8 | 67.7 | |
| Lymphocytes, % | 18.0–48.0 | 20.7 | 22.3 | |
| Monocytes, % | 4.0–15.0 | 6.6 | 7.1 | |
| Eosinophils, % | 0.0–8.0 | 0.2 | 0.2 | |
| Basophils, % | 0.0–1.9 | 0.04 | 0.02 | |
| Immunology | ||||
| ANA screen | Negative <1:80 | Negative <1:80 | ||
| Complement (C3), mg/dL | 50–180 | N/R | N/R | 148 |
| Complement (C4), mg/dL | 11–44 | N/R | N/R | 25 |
| Antistreptolysin O titer, IU/mL | <200 | 113 | ||
| C-ANCA | <1:20 titer | <1:20 titer | ||
| P-ANCA | <1:20 titer | <1:20 titer | ||
| Infectious disease | ||||
| Hepatitis B surface antigen | Negative | |||
| Urine | ||||
| Color | Yellow, straw, amber | Yellow | Yellow | |
| Appearance | Clear | Cloudy | Hazy | |
| Specific gravity | 1.005–1.030 | ≥1.030 | 1.025 | |
| pH | 5.0–8.0 | 5.0 | 5.0 | |
| Glucose | Negative | Negative | Negative | |
| Protein | Negative | Negative | 2+ | |
| Ketones | Negative | Negative | Negative | |
| Occult blood | Negative | Negative | 2+ | |
| Nitrite | Negative | Negative | Negative | |
| Bilirubin | Negative | Negative | Negative | |
| Leukocytes, hpf | 0–4 | Trace | Trace | |
| Red blood cells, hpf | 0–5 | 10 | ||
| White blood cells, hpf | None-Occ | 3 | 18 | |
| Bacteria | Rare | None | ||
| Protein to creatinine ratio, g/day | 0.00–0.20 | 1.1 |
↵aClinical chemistry and complete blood count were not done 3 weeks after the second dose of vaccine.
ANA, antinuclear antibody; C-ANCA, cytoplasmic-antineutrophil cytoplasmic antibodies; eGFR, estimated glomerular filtration rate; N/R, not reported; P-ANCA, perinuclear-antineutrophil cytoplasmic antibodies.