PaperD-Dimer plasma concentration in various clinical conditions: Implication for the use of this test in the diagnostic approach of venous thromboembolism
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2016, Biosensors and BioelectronicsCitation Excerpt :D-dimer is a protein created by degradation of the fibrin molecule (Gaffney 1973, 1993). Elevated levels of D-dimer in blood plasma have been related to severe pathological conditions like pulmonary embolism, septicemia, cirrhosis, carcinoma and sickle cell disease (Raimondi et al., 1993; Wakai et al., 2003). Studies have indicated that D-dimer can be also used as a marker for arterial and venous thrombosis and the prediction of cardiovascular disease.
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