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Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss

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Abstract

Longer duration of morbid obesity is associated with higher LV mass, poorer LV systolic function, and greater impairment of LV diastolic filling. Weight loss-induced decreases in LV mass and improvements in LV systolic function and diastolic filling are due in part to favorable alterations in LV loading conditions.

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Dr. Alpert's address is: Division of Cardiology, Suite 10C, University of South Alabama Medical Center, 2451 Fillingim Street, Mobile, Alabama 36617.

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