NeoplasmSpinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature
Section snippets
Selection of patients
An analysis of the clinical records of patients who underwent surgery for primitive intraspinal tumor at the Department of Neurosurgery of Florence included retrieval of the series of spinal neurinomas treated during the period between 1967 and 1997. We purposely limited the retrospective study to obtain at least 5 years of follow-up. Therefore, 20 neurinomas treated between 1997 and 2002 were excluded.
All the tumors that were surgically excised were reexamined using new histopathological
Statistics
There were 179 spinal neurinomas in 152 patients treated: 93 (61.18%) male and 59 (38.82%) female. The mean age was 44.3 (minimum 7, maximum of 80). Minimal difference in the relation between age and level of the lesion was observed. More precisely, the mean age in cervical lesions was 45.4, in the dorsal lesions 48.9, and in the lumbo-sacral lesions 43.2. Thirteen patients underwent surgery at an age <20 (8.55%). Eleven (7.23%) had Recklinghausen's neurofibromatosis (7 cases of NF1 and 4 of
Discussions and considerations
The neurinomas are the most frequent primal tumors of the spine 39, 54, 58, 76, 77, 84; there is no significant prevalence in literature between males and females [77]. In our series, on the contrary, we noted a clear prevalence in males, 93 cases (61.18%), with respect to females, 59 cases (38.82%). The age of manifestation in the different case reports varies between the 3rd and the 4th decade 39, 77. The site of the lesion is mostly intradural, less frequently extradural or dumbbell, and
References (89)
- et al.
Intramedullary ancient schwannoma of the cervical spinal cordcase report and review of literature
J Clin Neurosci
(2002) - et al.
Chiari type I malformation with an associated intramedullary schwannoma
Surg Neurol
(1985) - et al.
Intramedullary and extramedullary schwannoma of the cervical spinal cordcase report
Surg Neurol
(1989) - et al.
Mobile neurinoma of the cervicothoracic junction
Surg Neurol
(1998) - et al.
Radical resection of intramedullary spinal cord tumors without cavitron ultrasonic aspirator or CO2 lasera “two stage”
Surg Neurol
(1996) - et al.
Intramedullary spinal cord tumors
Surg Clin North Am
(1959) - et al.
Solitary intramedullary schwannomas
Surg Neurol
(1983) - et al.
Intramedullary melanotic schwannoma of the cervical spinereport of a case
Surg Neurol
(1990) - et al.
Cervical intramedullary schwannoma
Surg Neurol
(1981) - et al.
Intramedullary melanotic schwannoma. Report of a case and review of the literature
Br J Neurosurg
(1999)
Intramedullary nerve fiber and Schwann cell proliferation within the spinal cord (schwannosis)
Neurology
Gene for von Recklinghausen neurofibromatosis in the pericentromeric region of chromosome 17
Science
Intraparenchymal schwannomas of the central nervous systeman additional case report and review
Neurosurg Rev
Intramedullary schwannoma
Proc Inst Neurol, Madras
Multiple intramedullary schwannomascase report
Neurol Med Chir (Tokyo)
Intramedullary schwannoma of the spinal cord
J Neurosug Sci
Spinal cord schwannomacase report
Ar Qneuropsiquiatr
Syndrome cordonal postérieur unilatéral par neurinome intra-médullaire. Syncinésies homolatérales d'imitation
Rev Neurol
Intramedullary spinal neurinomas. Report of two cases
J Neurosurg
Primary spinal malignant schwannomasclinical and prognostic remarks
Acta Neurochir (Wien)
A long fallow-up study of 128 cases of intramedullary spinal cord tumors
Neurol Med Chir (Tokyo)
Spinal meningiomas in pregnancyreport of two cases and review of the literature
Eur J Gynaec Oncol XVII
Le alterazioni radiografiche nelle compressioni spinali in eta' infantile
Riv di Neuroradiologia
Tumore maligno della guaina dei nervi periferici (MPNST) post-irradiazione
Pathologica
Intramedullary schwannoma
Can Assoc Radiol J
Neurinoma intramedullar dorsal. Presentacion de un caso
Clin Neurochir
Intramedullary spinal neurofibroma diagnosed with computed tomographyreport of the case
Neurosurgery
Intramedullary tumors of the spinal cord
Acta Neurochir
I tumori intramidollari. Il Lavoro
Neuropsichiatrico
Solitary dorsal intramedullary schwannoma
J Neurosurg
Intramedullary spinal cord tumors resected with CO2 laser microsurgical techniquerecent experience in fifteen patients
Neurosurgery
Spinal subpial schwannoma
Neurol Med Chir (Tokyo)
Neurinoma cervicale intramidollare, descrizione di un caso e revisione della letteratura
Minerva Chir
Mobile Schwannoma of the cauda equina diagnosed by magnetic resonance imaging
Neurosurgery
A case of intramedullary spinal schwannoma
No Scinkei Gika
Neurinome Intramedullaire, a propos d'un cas. Revue de la litterature
Neurochirurgie
Intramedullary spinal schwannoma
J Neurol Neurosurg Psychiatry
The clinical evaluation of chemotherapeutic agents in cancer
Intramedullary tumors of the spinal cord
Arch Neurol Psychiatr
Introduction of a score system for the clinical evaluation of patients with spinal processes
Acta Neurochir (Wien)
Surgery of spinal nerve sheat tumors with special reference to neurofibromatosis
Neurosurgery
Intramedullary Schwannoma of the spinal cordreport of two cases
Neuroradiology
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