Research LettersAirway function in infants newly diagnosed with cystic fibrosis
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Variability of lung clearance index in clinically stable cystic fibrosis lung disease in school age children
2018, Journal of Cystic FibrosisCitation Excerpt :MBW offers a non-invasive tool with good feasibility across all ages to detect early lung disease changes, and is of great interest to the paediatric CF community [4]. There are increasing evidence that in CF pulmonary deterioration starts early in life and can occur in the absence of respiratory symptoms [5,6]. Frequent pulmonary exacerbations (PEx) are associated with impaired quality of life, accelerated decline in pulmonary function and premature death [7,8].
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