Brief reportThe effects of postal and telephone reminders on compliance with pravastatin therapy in a national registry: results of the First Myocardial Infarction Risk Reduction Program
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The OPTIMIZE trial: Rationale and design of a randomized controlled trial of motivational enhancement therapy to improve adherence to statin medication
2016, Contemporary Clinical TrialsCitation Excerpt :A recent (2010) Cochrane review of interventions to improve adherence to lipid lowering medication identified 11 randomized controlled trials (RCTs) [24]. Eight RCTs (n = 6449) focused on statin medication and were associated with improvements in adherence between 2.3% and 24% with a mean of 7.4% [25–32]. Interventions generally used education [30,31], or patient reinforcement/reminders [25–29,32], which improved adherence by 7.8% and 7.2%, respectively.
Proportion and Risk Indicators of Nonadherence to Statin Therapy: A Meta-analysis
2012, Canadian Journal of CardiologyCitation Excerpt :The remaining 219 articles were subjected to methodological quality review, and as a result, 152 articles were rejected. In the end, 67 articles (53 cohorts and 14 RCTs) were accepted for meta-analysis (Supplemental Table S3).2,14-79 All decisions were unanimous.
Targeting cardiovascular medication adherence interventions
2012, Journal of the American Pharmacists AssociationCitation Excerpt :Three interventions44,52,59 made use of electronic systems including interactive computer-based home monitoring,44 interactive phone technology with tailored messages,59 and automated calls with structured messages and targeted nurse follow-up.52 One study in this group45 consisted mainly of postal and phone reminders but had patients reporting adherence directly to physicians at 3 months. There was no prespecified physician response to nonadherence; in this case, we assumed that discussion occurred or medication changes were administered if patients reported nonadherence directly to the physician.