Chorea associated with gabapentin use in an elderly man
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Cited by (10)
Movement disorders associated with antiseizure medications: A systematic review
2022, Epilepsy and BehaviorCitation Excerpt :The gabapentin dose was reduced in 3 patients while drug was discontinued in all other cases. In addition, some patients with myoclonus underwent dialysis [295,315,316] or received haloperidol, diphenhydramine, lorazepam, or procyclidine [289,290,304,305]. In all instances, the interventions resulted in resolution of symptoms.
Gabapentinoids: A review of the literature
2021, Toxicologie Analytique et CliniquePediatric Iatrogenic Movement Disorders
2018, Seminars in Pediatric NeurologyCitation Excerpt :Baclofen is another GABAergic medication that can induce chorea. The mechanism of induction of chorea with these medications is not precisely known, but hypotheses include the role of central dopaminergic pathways in the basal ganglia, drug-drug interactions in the setting of polypharmacy, and a possible genetic predisposition to movement disorders.10-18 Stimulant medications that are used in the treatment of ADHD are associated with induction of chorea.
Antiepileptic drugs
2011, Side Effects of Drugs AnnualCitation Excerpt :Gabapentin is excreted unchanged in the urine and its half-life, normally 5–9 hours, increases to up to 132 hours in anuria [114A]. Chorea in an elderly patient with anxiety resolved completely after gabapentin was withdrawn [115A]. A 75-year-old man with anxiety disorder developed choreiform movements involving the neck, trunk, upper and lower limbs, and tongue after taking gabapentin 300 mg three times a day (tds) for 1 month.
Diagnostic Uncertainties: Chorea
2023, Seminars in Neurology