Original articleAdult cardiacOutcomes on Continuous Flow Left Ventricular Assist Devices: A Single Institutional 9-Year Experience
Section snippets
Material and Methods
Our health system’s institutional review board approved this retrospective study. We reviewed our institution’s LVAD data set and analyzed patients who underwent CF LVAD implantation as a BTT or DT from March 2006 through May 2015. Two hundred thirty-one patients who underwent 240 device implants (9 were device exchanges) were identified and formed the cohort of this study. Patients received either HeartMate II LVADs (n = 205) or HeartWare HVADs (n = 35).
Demographic and Operative Characteristics of LVAD Recipients
Mean age of our overall patient cohort was 54.5 ± 12.1 years (range, 17 to 81 years), 25.4% were women, and the indication for LVAD implantation was 52.9% in the BTT cohort and 47.1% in the DT cohort. Patients who received LVAD therapy as a BTT were significantly younger (51.2 ± 11.9 versus 58.2 ± 11.4 years, p < 0.001). Additional demographic characteristics and comorbidities are summarized in Table 1. Patients in the BTT cohort were more likely to have nonischemic dilated cardiomyopathy as
Comment
Continuous flow LVADs have substantially altered the expected survival for patients with end-stage heart failure refractory to optimal medical therapy 11, 12, 13. Patients implanted as a BTT or DT have substantially increased survival compared with patients implanted with the older generation HeartMate XVE device [11]. However, both the HM II and HVAD devices are associated with a relatively high incidence of device-related complications, such as GIB, RV failure, stroke, and DL infections 14, 15
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