High Intrapatient Variability of Tacrolimus Concentrations Predicts Accelerated Progression of Chronic Histologic Lesions in Renal Recipients
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Key words
clinical research/practice
immunosuppression/immune modulation
kidney transplantation/nephrology
pharmacology
fibrosis
immunosuppressant
calcineurin inhibitor: tacrolimus
kidney (allograft) function/dysfunction
pharmacokinetics/pharmacodynamics
Abbreviations
C0/D
dose-corrected concentration
CI
confidence interval
CV
coefficient of variability
DBD
donation after brain death
DCD
donation after cardiac death
DSA
donor-specific antibody
eGFR
estimated GFR
IPV
intrapatient variability
MMF
mycophenolate mofetil
MVI
microvascular inflammation
OR
odds ratio
PRA
panel reactive antibody
SD
standard deviation
Cited by (0)
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Both authors contributed equally to this article.
Copyright © 2016 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.