Chest
Volume 109, Issue 1, January 1996, Page 292
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Communications to the Editor
Lactic Acidosis Associated With Propofol

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To the Editor

Propofol is a short-acting IV anesthetic agent used for induction of general anesthesia and sedation of mechanically ventilated patients.1, 2 Propofol has a rapid onset and termination of action making it attractive for use in the ICU. Adverse effects include hypotension, green discoloration of urine, sepsis, and anaphylactoid reactions.1, 2, 3 This letter describes a patient with severe asthma who required mechanical ventilation and temporarily developed lactic acidosis while being sedated

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