Abstract
Xanthogranulomatous osteomyelitis is a rare chronic inflammatory disorder which clinically resembles bone tumor. It is characterized histologically by the presence of a large number of foamy histiocytes admixed with lymphocytes and plasma cells. Xanthogranulomatous inflammation can involve any organ, with kidneys and gall bladder being the worst affected. Only anecdotal cases of osteomyelitis have been reported in the past with scant medical literature. However, all the earlier reported cases, except one, were unifocal lesions. The authors present a case of multifocal xanthogranulomatous osteomyelitis involving the left medial malleoli, left talus and the right cuboid bones.
Similar content being viewed by others
References
Cozzutto C. Xanthogranulomatous osteomyelitis. Arch Pathol Lab Med 1984;108:973–6.
Vankalakunti M, Saikia UN, Mathew M, Kang M. Xanthogranulomatous osteomyelitis of ulna mimicking neoplasm. World J Surg Oncol 2007;5:46.
Cennimo DJ, Agag R, Fleegler E, Lardizabal A, Klein KM, Wenokor C, et al. Mycobacterium marinum Hand Infection in a “Sushi Chef”. Eplasty 2009;9:e43.
Borjian A, Rezaei F, Eshaghi MA, Shemshaki H. Xanthogranulomatous osteomyelitis. J Orthop Traumatol 2012;13:217–20.
Kamat G, Gramapurohit V, Myageri A, Shettar C. Xanthogranulomatous osteomyelitis presenting as swelling in right tibia. Case Rep Pathol 2011;2011:257458.
Lee SH, Lee YH, Park H, Cho YJ, Song HT, Yang WI, et al. A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm. Am J Case Rep 2013;14:304–7.
Kashani MM, Zakerian BZ, Shayan K, Riyasi F. Xanthogranulomatous osteomyelitis of femur. Iran J Orthop Surg 2010;8:187–90.
Wang YL, Yu H, Zhang H, Cui XJ, Han JK. Xanthogranulomatous osteomyelitis of rib mimicking malignant lesions in (18) F-FDG PET/CT imaging: A report of two cases. Clin Nucl Med 2014;39:e315–7.
Holmes BJ, Castelino-Prabhu S, Rosenthal DL, Ali SZ. Xanthogranuloma of bone: A challenging imitator of malignancy. Acta Cytol 2013;57:198–202.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Sapra, R., Jain, P., Gupta, S. et al. Multifocal bilateral xanthogranulomatous osteomyelitis. IJOO 49, 482–484 (2015). https://doi.org/10.4103/0019-5413.159682
Published:
Issue Date:
DOI: https://doi.org/10.4103/0019-5413.159682