The barrier effect of laminae: laminotomy versus laminectomy

Spinal Cord. 2000 Jul;38(7):442-4. doi: 10.1038/sj.sc.3101029.

Abstract

Study design: An experimental study to investigate whether replacement of the laminae (laminotomy) after subliminal procedures can prevent the invasion of scar tissue towards the dura.

Setting: Izmir, Turkey.

Methods: Laminectomy and laminotomy were performed at different levels on seven rats. Their spinal columns were investigated histopathologically after a period of 3 months.

Results: The histopathological evaluation revealed that the dura and spinal cord were involved by scar tissue at laminectomy area. However, this invasion was not observed at laminotomy levels. This study showed the barrier effect of laminae against fibroblastic activity.

Conclusion: The barrier effect of lamina may affect the surgical outcome related to epidural fibrosis.

MeSH terms

  • Animals
  • Cicatrix / pathology
  • Cicatrix / physiopathology
  • Cicatrix / prevention & control
  • Dura Mater / pathology
  • Dura Mater / physiopathology
  • Dura Mater / surgery
  • Epidural Space / pathology
  • Epidural Space / physiopathology
  • Epidural Space / surgery
  • Laminectomy / adverse effects*
  • Laminectomy / methods*
  • Male
  • Postoperative Complications / prevention & control*
  • Rats
  • Spinal Cord / pathology
  • Spinal Cord / physiopathology
  • Spinal Cord / surgery
  • Spinal Cord Injuries / pathology
  • Spinal Cord Injuries / physiopathology
  • Spinal Cord Injuries / surgery
  • Spine / pathology
  • Spine / physiopathology
  • Spine / surgery*