Hughes (antiphospholipid) syndrome. Clinical features

Rheum Dis Clin North Am. 2001 Aug;27(3):507-24, v. doi: 10.1016/s0889-857x(05)70217-9.

Abstract

Hughes (antiphospholipid) syndrome is a noninflammatory autoimmune disease. The most critical pathologic process is thrombosis, which results in most of the clinical features suffered by these patients. Recurrent thrombosis together with an adverse pregnancy history and the presence of antiphospholipid antibodies defines the syndrome.

MeSH terms

  • Antibodies, Antiphospholipid / analysis
  • Antiphospholipid Syndrome / diagnosis
  • Antiphospholipid Syndrome / pathology*
  • Central Nervous System Diseases / etiology
  • Central Nervous System Diseases / pathology
  • Diagnosis, Differential
  • Female
  • Hematologic Diseases / etiology
  • Hematologic Diseases / pathology
  • Humans
  • Lung Diseases / etiology
  • Lung Diseases / pathology
  • Pregnancy
  • Pregnancy Complications
  • Skin Diseases / etiology
  • Skin Diseases / pathology
  • Thrombosis / etiology*

Substances

  • Antibodies, Antiphospholipid