Radiation-associated valvular heart disease in Hodgkin's disease is associated with characteristic thickening and fibrosis of the aortic-mitral curtain

M D Brand; C A Abadi; G P Aurigemma; H L Dauerman; T E Meyer

Radiation-associated valvular heart disease in Hodgkin's disease is associated with characteristic thickening and fibrosis of the aortic-mitral curtain

J Heart Valve Dis. 2001 Sep;10(5):681-5.

Authors

M D Brand¹, C A Abadi, G P Aurigemma, H L Dauerman, T E Meyer

Affiliation

¹ Cardiovascular Division, University of Massachusetts-Memorial Medical Center and University of Massachusetts Medical School, Worcester 01655, USA.

PMID: 11603609

Abstract

Radiation-associated valvular dysfunction is characterized by variable aortic and mitral valve thickening. A review of three patients assessed echocardiographically revealed that radiation-associated valvular dysfunction after radiation treatment for Hodgkin's disease may be characterized by a unique and consistent pattern of thickening of the aortic and mitral valves involving the aortic-mitral curtain.

Publication types

Case Reports

MeSH terms

Aortic Valve / radiation effects*
Female
Heart Valve Diseases / etiology*
Heart Valve Diseases / mortality
Hodgkin Disease / complications*
Hodgkin Disease / mortality
Hodgkin Disease / radiotherapy*
Humans
Male
Middle Aged
Mitral Valve / radiation effects*
Radiation Pneumonitis / complications*
Radiation Pneumonitis / mortality
Treatment Failure