Dietary sodium intake and arterial blood pressure

J Ren Nutr. 2009 Jan;19(1):57-60. doi: 10.1053/j.jrn.2008.10.006.

Abstract

We sought to summarize major recent studies in the field of dietary sodium intake and arterial blood pressure, and discuss the following trials. INTERSALT: Sodium intake correlates with the rise in blood pressure with age, but not with the prevalence of hypertension. The population study identified a minimal impact of sodium intake on blood pressure (0.9 mm Hg/10 mmol difference in salt intake). DASH: This diet induced significant reductions in blood pressure compared with the control diet. Further decreases were observed with DASH and a 50 mmol/day sodium intake. VANGUARD: Blood pressure was inversely related to urinary potassium, calcium and magnesium but not to sodium excretion. TONE: Cardiovascular events were highest in the usual care group (83%) and lowest in the sodium reduction-plus-weight loss group (56%). META-ANALYSIS: A systematic review of 11 long-term controlled randomized trials reported a small decrease (1.1 mm Hg) in median systolic but not diastolic blood pressure with a reduced dietary sodium intake. In conclusion, (1) sodium restriction in hypertensive patients reduces blood pressure, and (2) the long-term impact of reduced salt intake on blood pressure, mortality, and morbidity remains to be defined.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Aging
  • Blood Pressure / drug effects*
  • Blood Pressure / physiology
  • Calcium / urine
  • Cardiovascular Diseases / prevention & control
  • Diastole
  • Diet, Sodium-Restricted*
  • Humans
  • Hypertension / diet therapy
  • Hypertension / epidemiology
  • Hypertension / etiology
  • Hypertension / physiopathology*
  • Kidney Failure, Chronic / diet therapy
  • Kidney Failure, Chronic / etiology*
  • Kidney Failure, Chronic / prevention & control
  • Magnesium / urine
  • Potassium / urine
  • Randomized Controlled Trials as Topic
  • Sodium Chloride, Dietary / administration & dosage*
  • Systole
  • Weight Loss / physiology

Substances

  • Sodium Chloride, Dietary
  • Magnesium
  • Potassium
  • Calcium