Abstract
Ketorolac tromethamine (0.5 mg kg-1) was given intravenously to 10 children (age 4-8 years) after minor surgery. Values of steady-state volume of distribution and plasma clearance were approximately two times higher than those in adults but values of elimination half-life were similar.
MeSH terms
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Anesthesia
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Child
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Child, Preschool
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Drug Combinations
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Female
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Half-Life
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Humans
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Injections, Intravenous
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Ketorolac Tromethamine
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Male
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Postoperative Period
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Preanesthetic Medication
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Tolmetin / administration & dosage
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Tolmetin / analogs & derivatives*
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Tolmetin / pharmacokinetics
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Tromethamine / administration & dosage
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Tromethamine / pharmacokinetics*
Substances
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Drug Combinations
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Tromethamine
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Ketorolac Tromethamine
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Tolmetin