User profiles for Amy Duffield
 | Amy DuffieldIcahn School of Medicine at Mount Sinai Hospital Verified email at mountsinai.org Cited by 2530 |
[HTML][HTML] Long interspersed element-1 protein expression is a hallmark of many human cancers
Cancers comprise a heterogeneous group of human diseases. Unifying characteristics
include unchecked abilities of tumor cells to proliferate and spread anatomically, and the …
include unchecked abilities of tumor cells to proliferate and spread anatomically, and the …
International Consensus Classification of acute lymphoblastic leukemia/lymphoma
The updated International Consensus Classification (ICC) of B-acute lymphoblastic leukemia
(B-ALL) and T-acute lymphoblastic leukemia (T-ALL) includes both revisions to subtypes …
(B-ALL) and T-acute lymphoblastic leukemia (T-ALL) includes both revisions to subtypes …
Radical prostatectomy findings in patients in whom active surveillance of prostate cancer fails
AS Duffield, TK Lee, H Miyamoto, HB Carter… - The Journal of …, 2009 - auajournals.org
Purpose : Little data are available on radical prostatectomy findings in men who experience
disease progression following active surveillance. Materials and Methods : A total of 470 …
disease progression following active surveillance. Materials and Methods : A total of 470 …
[HTML][HTML] FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation
Tyrosine kinase inhibitors (TKIs) targeting FLT3 have shown activity but when used alone
have achieved limited success in clinical trials, suggesting the need for combination with other …
have achieved limited success in clinical trials, suggesting the need for combination with other …
Cancer spectrum and outcomes in the Mendelian short telomere syndromes
Short telomeres have been linked to cancer risk, yet other evidence supports them being
tumor suppressive. Here, we report cancer outcomes in individuals with germline mutations in …
tumor suppressive. Here, we report cancer outcomes in individuals with germline mutations in …
The tetraspanin CD63 enhances the internalization of the H, K-ATPase β-subunit
A Duffield, EJ Kamsteeg, AN Brown… - Proceedings of the …, 2003 - National Acad Sciences
The tetraspanin CD63 resides in late endosomes, lysosomes, secretory vesicles, and at the
plasma membrane, and it moves among these compartments. We find that CD63 is present …
plasma membrane, and it moves among these compartments. We find that CD63 is present …
A multi-center phase I trial of ipilimumab in patients with myelodysplastic syndromes following hypomethylating agent failure
Purpose: After failure of hypomethylating agents (HMA), patients with myelodysplastic syndromes
(MDS) have dismal survival and no approved treatment options. Patients and Methods: …
(MDS) have dismal survival and no approved treatment options. Patients and Methods: …
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model
…, B Nguyen, R Novak, A Duffield… - Blood, The Journal …, 2012 - ashpublications.org
Constitutive activation of FLT3 by internal tandem duplication (ITD) is one of the most common
molecular alterations in acute myeloid leukemia (AML). FLT3/ITD mutations have also …
molecular alterations in acute myeloid leukemia (AML). FLT3/ITD mutations have also …
[HTML][HTML] CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma
…, A Pallavajjala, S Pittaluga, ES Jaffe, AS Duffield… - Blood cancer …, 2020 - nature.com
The diffuse variant of follicular lymphoma (dFL) is a rare variant of FL lacking t(14;18) that was
first described in 2009. In this study, we use a comprehensive approach to define unifying …
first described in 2009. In this study, we use a comprehensive approach to define unifying …
[HTML][HTML] Deep learning for diagnosis of acute promyelocytic leukemia via recognition of genomically imprinted morphologic features
…, A Luo, BC Hambley, J Bynum, AS Duffield… - NPJ precision …, 2021 - nature.com
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML), classified
by a translocation between chromosomes 15 and 17 [t(15;17)], that is considered a true …
by a translocation between chromosomes 15 and 17 [t(15;17)], that is considered a true …