Sphingolipids (SLs) are essential components of cellular membranes formed from the
condensation of l-serine and a long-chain acyl thioester. This first step is catalyzed by the pyridoxal…

Purpose: Excessive scarring leading to failure of the filtering bleb continues to be a major
problem after glaucoma filtration surgery. This study examines the antifibrotic effects of the anti-…

Clinical Relevance Late complications can occur with use of current antimetabolites to
prevent scarring following glaucoma filtration surgery (GFS). Safer, more targeted, anti-fibrosis …

The pyridoxal 5′-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT) is
required for de novo sphingolipid biosynthesis. A previous study revealed a novel and …

Serine palmitoyltransferase (SPT) catalyses the first committed step of de novo sphingolipid
biosynthesis. The bacterial SPT homologue from Sphingomonas paucimobilis is a …

The pyridoxal 5′-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT)
catalyses the first step of de novo sphingolipid biosynthesis. The core human enzyme is a …

Purpose.: We compared the anti-fibrotic effects of single versus multiple postoperative injections
of saratin following glaucoma filtration surgery (GFS) in the rabbit model. Methods.: The …

Hypochondriacal patients are always a challenge. They require an overabundance of
physicians’ time; they are responsible for excessive healthcare dollars; they demand extensive …

This paper examines the role that employer branding takes in employee recruitment and
retention. This includes an in-depth look into social media in employer branding, and the use of …

We report the results of a collaborative decision making exercise using a simulated stability
operations task. The exercise allowed Canadian Forces personnel to experience first-hand …