Incidence of cardiovascular events and gastrointestinal bleeding in patients receiving clopidogrel with and without proton pump inhibitors: an updated meta-analysis

…, JJ DiNicolantonio, DC Garcia, FYB Macedo… - Open …, 2015 - openheart.bmj.com
Background Dual antiplatelet therapy is the standard of care after coronary stent placement
but increases the bleeding risk. The effects of proton pump inhibitors (PPIs) on clopidogrel …

Cyclooxygenase-2 contributes to functional changes seen on experimental hemorrhagic cystitis induced by ifosfamide in rat urinary bladder

FYB Macedo, LTC Mourão, RC Palheta… - Cancer chemotherapy …, 2011 - Springer
Purpose Ifosfamide (IFS) is often involved in the occurrence of hemorrhagic cystitis due to
direct contact of its metabolite acrolein with uroepithelium. It has been shown that COX-2 is …

Metaanalysis of multivessel vs culprit artery only percutaneous coronary intervention in ST elevation myocardial infarction

…, CJ White, RN Cardoso, FYB Macedo… - Ochsner …, 2019 - ochsnerjournal.org
Background: Primary percutaneous coronary intervention (PCI) is the most frequently used
treatment modality for patients presenting with ST elevation myocardial infarction (STEMI). …

CATHETER-BASED RENAL SYMPATETIC DENERVATION FOR RESISTANT HYPERTENSION: A META-ANALYSIS OF CLINICAL TRIALS

D Garcia, FYB Macedo, A Benjo, E Aziz… - Journal of the American …, 2013 - jacc.org
Background Catheter ablation of the renal sympathetic innervations is promising therapy
but data is still limited. We aimed to evaluating its effectiveness in a meta-analysis of the …

DABIGATRAN CONSISTENTLY INCREASES THE RISK OF ACUTE CORONARY DISEASE: A RANDOMIZED-CONTROLLED TRIALS META-ANALYSIS

AM Benjo, F Nascimento, FYB Macedo, F Javed… - Journal of the American …, 2012 - jacc.org
Background Dabigatran is a direct thrombin inhibitor recently approved as an alternative to
warfarin. The approval, however, carried a recommendation to describe in the label a …

[HTML][HTML] c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype

V Florea, N Bhagavatula, G Simovic, FY Macedo… - PloS one, 2013 - journals.plos.org
The proto-oncogene c-Myc is vital for vascular development and promotes tumor angiogenesis,
but the mechanisms by which it controls blood vessel growth remain unclear. In the …

Correlation of right atrial enlargement on ECG to right atrial volume by echocardiography in patients with pulmonary hypertension

JD Allison, FY Macedo, IR Hamzeh… - Journal of …, 2017 - Elsevier
… Because measuring RAV has only recently become standard for assessing RA size, one
investigator (YB), without access to the ECG data, retrospectively analyzed all echocardiograms …

Natural film based on collagen and sulfated polysaccharide for antiplatelet effects

AAM Macêdo, SD Figueiró, JCG Ferreira… - … Journal of Polymer …, 2022 - Taylor & Francis
Although several properties of collagen have been explored, the blend formation with sulfated
polymers is poorly explored. Antiplatelet effects can be achieved after the formation of this …

Parenting, the other oldest profession in the world–a cross-sectional study of parenting and child outcomes in South Africa and Malawi

L Sherr, A Macedo, LD Cluver, F Meinck… - Health psychology …, 2017 - Taylor & Francis
Parenting quality is important in child development. In the presence of HIV poverty and life
stress, parenting may be challenged and child development affected. This study examines …

The histone lysine demethylase KDM7A is required for normal development and first cell lineage specification in porcine embryos

VB Rissi, WG Glanzner, MP De Macedo, K Gutierrez… - Epigenetics, 2019 - Taylor & Francis
There is growing evidence that histone lysine demethylases (KDMs) play critical roles in the
regulation of embryo development. This study investigated if KDM7A, a lysine demethylase …