The distinction between bactericidal and bacteriostatic agents appears to be clear according
to the in vitro definition, but this only applies under strict laboratory conditions and is …

New antimicrobial agents are urgently needed for clinical use due to the increasing prevalence
and spread of multidrug-resistant bacteria that are commonly responsible for serious and …

Background . Although a considerable amount of research has gone into the study of the
role of bactericidal versus bacteriostatic antimicrobial agents in the treatment of different …

Evidence-based guidelines for the diagnosis and initial management of suspected acute
bacterial rhinosinusitis in adults and children were prepared by a multidisciplinary expert panel …

Aspergillosis comprises a variety of manifestations of infection. These guidelines are
directed to 3 principal entities: invasive aspergillosis, involving several organ systems (particularly …

We conducted a case study of human immunodeficiency virus (HIV)-negative patients with
cryptococcosis at 15 United States medical centers from 1990 through 1996 to understand the …

Objective. —To assess the efficacy of adjunctive monoclonal antibody antiendotoxin
immunotherapy in patients with gram-negative sepsis. Design. —Double-blind, randomized, …

Cryptococcus neoformans is an uncommonly recognized cause of pneumonia in HIV-negative
patients. Because of its propensity to disseminate to the meninges and other sites, a …

Invasive aspergillosis occurred in 26 liver transplant recipients since 1990 at five liver
transplant centers. The median time to onset was 17 days after transplantation. Twenty-seven …

Nineteen patients with phaeohyphomycosis were treated with itraconazole. Of these, 17
were assessable for clinical outcome. Of these, two had received no prior therapy, five had …