Global status and conservation potential of reef sharks

…, P Matich, E McCombs, D McLean, L Meggs… - Nature, 2020 - nature.com
Decades of overexploitation have devastated shark populations, leaving considerable
doubt as to their ecological status 1 , 2 . Yet much of what is known about sharks has been …

Angiotensin II induces apoptosis of adult ventricular myocytesin vitro

…, E Cigola, A Malhotra, P Li, W Cheng, LG Meggs… - Journal of molecular and …, 1997 - Elsevier
To determine whether angiotensin II (Ang II) activates the suicide program of myocytes, primary
cultures of adult rat ventricular myocytes were exposed to 10 −9 mof Ang II, for 24 h. Ang …

Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart.

…, EH Sonnenblick, G Olivetti, LG Meggs… - Circulation …, 1990 - Am Heart Assoc
To determine the effects of age on the myocardium, the functional and structural characteristics
of the heart were studied in rats at 4, 12, 20, and 29 months of age. Mean arterial pressure…

Cellular basis of chronic ventricular remodeling after myocardial infarction in rats.

G Olivetti, JM Capasso, LG Meggs… - Circulation …, 1991 - Am Heart Assoc
To determine whether the hypertrophic response of the surviving myocardium after infarction
leads to normalization of ventricular hemodynamics and wall stress, the left coronary artery …

Sustained effectiveness of converting-enzyme inhibition in patients with severe congestive heart failure

…, GH Williams, G Curfman, L Meggs… - … England Journal of …, 1980 - Mass Medical Soc
Eight patients with severe congestive heart failure refractory to conventional therapy,
including vasodilators, were given captopril (seven patients) or teprotide (one patient). All had …

Angiotensin II promotes glucose-induced activation of cardiac protein kinase C isozymes and phosphorylation of troponin I

…, BPS Kang, S Cheung, D Opawumi, LG Meggs - Diabetes, 2001 - Am Diabetes Assoc
… The media was then replaced by SFM containing 25 mmol/l … SFM containing 5 mmol/l glucose
and 20 mmol/l mannitol. For … mmol/l Tris-HCl, 0.33 mol/l sucrose, 2 mmol/l EGTA, 2 mmol/l

High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism

…, A Kessler, A Malhotra, LG Meggs - American Journal …, 2003 - journals.physiology.org
… Culture conditions were as follows; NHMCs were maintained in mesangial cell basal
medium (MsGM, BioWhittaker), supplemented with 5% FBS, 30 mg/l gentamicin, and 15 μg/l

Angiotensin II Activates Programmed Myocyte Cell Deathin Vitro

E Cigola, J Kajstura, B Li, LG Meggs… - Experimental cell research, 1997 - Elsevier
To determine whether angiotensin II (Ang II) can induce apoptosis of neonatal ventricular
myocytes, these cells were exposed to 10 −9 MAng II for 24 hin vitroand the effects of this …

Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart

…, TJ Regan, SF Vatner, LG Meggs… - American Journal …, 2003 - journals.physiology.org
Aging and diabetes mellitus (DM) both affect the structure and function of the myocardium,
resulting in increased collagen in the heart and reduced cardiac function. As part of this …

Widespread diversity deficits of coral reef sharks and rays

…, P Matich, E McCombs, A McIvor, D McLean, L Meggs… - Science, 2023 - science.org
A global survey of coral reefs reveals that overfishing is driving resident shark species toward
extinction, causing diversity deficits in reef elasmobranch (shark and ray) assemblages. …