Smooth muscle regional contribution to vaginal wall function
…, DJ Lawrence, SH Lindsey, L Desrosiers… - Interface …, 2019 - royalsocietypublishing.org
Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal
canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although …
canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although …
Biaxial mechanical assessment of the murine vaginal wall using extension–inflation testing
…, CK Conway, L Desrosiers… - Journal of …, 2017 - asmedigitalcollection.asme.org
Progress toward understanding the underlying mechanisms of pelvic organ prolapse (POP)
is limited, in part, due to a lack of information on the biomechanical properties and …
is limited, in part, due to a lack of information on the biomechanical properties and …
The evolution of evaluation and management of urinary or fecal incontinence and pelvic organ prolapse
…, A Garely, N Noor, L Desrosiers… - Current problems …, 2015 - pubmed.ncbi.nlm.nih.gov
… Scott R Steele, Madhulika G Varma, David Prichard, Adil E Bharucha, Sarah A Vogler,
Askin Erdogan, Satish SC Rao, Ann C Lowry, Erin O Lange, Glen M Hall, Joshua IS Bleier …
Askin Erdogan, Satish SC Rao, Ann C Lowry, Erin O Lange, Glen M Hall, Joshua IS Bleier …
Effects of elastase digestion on the murine vaginal wall biaxial mechanical response
…, DJ Capone, L Desrosiers… - Journal of …, 2019 - asmedigitalcollection.asme.org
Although the underlying mechanisms of pelvic organ prolapse (POP) remain unknown,
disruption of elastic fiber metabolism within the vaginal wall extracellular matrix (ECM) has been …
disruption of elastic fiber metabolism within the vaginal wall extracellular matrix (ECM) has been …
[HTML][HTML] Role of fibulin-5 insufficiency and prolapse progression on murine vaginal biomechanical function
GL Clark-Patterson, S Roy, L Desrosiers, LR Knoepp… - Scientific Reports, 2021 - nature.com
The vagina plays a critical role in supporting the pelvic organs and loss of support leads to
pelvic organ prolapse. It is unknown what microstructural changes influence prolapse …
pelvic organ prolapse. It is unknown what microstructural changes influence prolapse …
[HTML][HTML] Pelvic organ prolapse: a review of in vitro testing of pelvic support mechanisms
…, GL Clark-Patterson, KS Miller, L Desrosiers… - Ochsner …, 2020 - ochsnerjournal.org
Background: Pelvic organ prolapse (POP) affects a significant portion of the female population,
impacting quality of life and often requiring intervention. The exact cause of prolapse is …
impacting quality of life and often requiring intervention. The exact cause of prolapse is …
[HTML][HTML] Comparison of biaxial biomechanical properties of post-menopausal human prolapsed and non-prolapsed uterosacral ligament
…, I Johnson, EW Harville, LR Buckner, L Desrosiers… - Scientific Reports, 2020 - nature.com
Uterosacral ligaments (USLs) provide structural support to the female pelvic floor, and a
loss of USL structural integrity or biomechanical function may induce pelvic organ prolapse (POP…
loss of USL structural integrity or biomechanical function may induce pelvic organ prolapse (POP…
Evaluating residual strain throughout the murine female reproductive system
Mounting evidence suggests that cells within soft tissues seek to maintain a preferred
biomechanical state. Residual stress is defined as the stress that remains in a tissue when all …
biomechanical state. Residual stress is defined as the stress that remains in a tissue when all …
Direct intracellular measurement of deoxygenated hemoglobin S solubility
ME Fabry, L Desrosiers… - Blood, The Journal of the …, 2001 - ashpublications.org
The solubility of deoxygenated hemoglobin S (HbS), which is the concentration of fully
deoxygenated HbS in equilibrium with polymer (C SAT ), is a factor that determines in vivo …
deoxygenated HbS in equilibrium with polymer (C SAT ), is a factor that determines in vivo …
Biaxial biomechanical properties of the nonpregnant murine cervix and uterus
…, HJ Qureshi, VL Morris, EK Danso, L Desrosiers… - Journal of …, 2019 - Elsevier
From a biomechanical perspective, female reproductive health is an understudied area of
research. There is an incomplete understanding of the complex function and interaction …
research. There is an incomplete understanding of the complex function and interaction …