The protein product of the bcl‐2 gene is thought to be involved in inhibition of apoptosis; it
may therefore be important in the modulation of hormonal/anti‐hormonal responsiveness …

BACKGROUND: It is unclear whether breast cancer has a similar prognosis in males and
females. METHODS: A 20-year retrospective study of all male breast cancer patients in our …

Acute cholecystitis is increasingly managed by laparoscopic cholecystectomy. Some reports
have shown conversion and complication rates that are increased in comparison to elective …

The tissue expression of c-erbB-2 protein in breast cancer is a marker of poor prognosis in a
number of studies. More recently it has also been suggested that c-erbB-2 expression may …

Background: Intraoperative subareolar frozen sections are used to assess the nipple areolar
complex9s suitability for preservation for patients selected for nipple-sparing mastectomy. …

Objectives The objective of this study was to evaluate patient compliance with management
recommendations given by a breast cancer multidisciplinary team (MDT), assess for reasons …

Pre-treatment oestrogen receptor (ER) expression in breast cancer predicts for rate of response
to endocrine therapy but not for the quality or duration of response (DofR). ER is known …

Multiple papillomas (MP) are subject to debate in terms of their clinical and pathological
significance and management. To date the ideal management is still not well established. The …

Background Overall survival of HER2 positive metastatic breast cancer patients has been
significantly improved with inclusion of trastuzumab to chemotherapy. Several studies have …

Objective Breast cancer (BC) accounts for 24% of female cancers, with approximately one
quarter of women likely to have offspring aged less than 25 years. Recent publications …