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Review ArticleReviews and Commentaries

Rhabdomyolysis: Pathogenesis, Diagnosis, and Treatment

Patrick A. Torres, John A. Helmstetter, Adam M. Kaye and Alan David Kaye
Ochsner Journal March 2015, 15 (1) 58-69;
Patrick A. Torres
1Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA
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John A. Helmstetter
1Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA
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Adam M. Kaye
2Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA
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Alan David Kaye
1Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA
3Department of Pharmacology, Louisiana State University Health Sciences Center, New Orleans, LA
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Abstract

Background Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.

Methods This review focuses on the epidemiology, pathophysiology, causes, presentation, diagnosis, complications, management, and anesthetic considerations related to rhabdomyolysis.

Results Any form of muscle damage––and by extension any entity that causes muscle damage––can initiate rhabdomyolysis. One of the most important treatment goals when rhabdomyolysis is suspected is avoiding acute kidney injury.

Conclusion All clinicians should be aware of common causes, diagnosis, and treatment options.

Keywords
  • Rhabdomyolysis

Footnotes

  • The authors have no financial or proprietary interest in the subject matter of this article.

  • © Academic Division of Ochsner Clinic Foundation
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Rhabdomyolysis: Pathogenesis, Diagnosis, and Treatment
Patrick A. Torres, John A. Helmstetter, Adam M. Kaye, Alan David Kaye
Ochsner Journal Mar 2015, 15 (1) 58-69;

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Rhabdomyolysis: Pathogenesis, Diagnosis, and Treatment
Patrick A. Torres, John A. Helmstetter, Adam M. Kaye, Alan David Kaye
Ochsner Journal Mar 2015, 15 (1) 58-69;
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