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Research ArticleFocus on Women and Children

Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease

Solo Kuvibidila, Rajasekharan P. Warrier, Johnson Haynes and Surendra B. Baliga
Ochsner Journal September 2015, 15 (3) 241-247;
Solo Kuvibidila
Department of Pediatrics, Louisiana State University Health Sciences Center, New Orleans, LA
Division of Research, The Research Institute for Children, Children's Hospital, New Orleans, LA
PhD
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Rajasekharan P. Warrier
Department of Pediatrics, Division of Hematology/Oncology, Louisiana State University Health Sciences Center, New Orleans, LA
Department of Pediatric Hematology/Oncology, Ochsner Clinic Foundation, New Orleans, LA
The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA
MD
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Johnson Haynes
Department of Pediatrics and The Sickle Cell Center, University of South Alabama College of Medicine, Mobile, AL
MD
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Surendra B. Baliga
Department of Pediatrics and The Sickle Cell Center, University of South Alabama College of Medicine, Mobile, AL
PhD
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Article Information

vol. 15 no. 3 241-247
PubMed 
26412995

Published By 
Ochsner Journal
Print ISSN 
1524-5012
Online ISSN 
1524-5012
History 
  • Published online September 1, 2015.

Copyright & Usage 
© Academic Division of Ochsner Clinic Foundation

Author Information

  1. Solo Kuvibidila, PhD1,2,
  2. Rajasekharan P. Warrier, MD3,4,5,
  3. Johnson Haynes, MD6 and
  4. Surendra B. Baliga, PhD6
  1. Department of Pediatrics, Louisiana State University Health Sciences Center, New Orleans, LA
  2. Division of Research, The Research Institute for Children, Children's Hospital, New Orleans, LA
  3. Department of Pediatrics, Division of Hematology/Oncology, Louisiana State University Health Sciences Center, New Orleans, LA
  4. Department of Pediatric Hematology/Oncology, Ochsner Clinic Foundation, New Orleans, LA
  5. The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA
  6. Department of Pediatrics and The Sickle Cell Center, University of South Alabama College of Medicine, Mobile, AL
  1. Address all correspondence to Rajasekharan P. Warrier, MD, FAAP, FIAP, Department of Pediatric Hematology/Oncology, Ochsner Clinic Foundation, 1315 Jefferson Hwy., New Orleans, LA 70121. Tel: (504) 842-5230. E-mail: rwarrier{at}ochsner.org
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Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease
Solo Kuvibidila, Rajasekharan P. Warrier, Johnson Haynes, Surendra B. Baliga
Ochsner Journal Sep 2015, 15 (3) 241-247;

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Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease
Solo Kuvibidila, Rajasekharan P. Warrier, Johnson Haynes, Surendra B. Baliga
Ochsner Journal Sep 2015, 15 (3) 241-247;
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Keywords

  • Anemia–sickle cell
  • hydroxyurea
  • interleukin-2
  • mice
  • zileuton

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