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Review ArticleReviews and Contemporary Updates

Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection

Mark F. McCarty, James H. O'Keefe and James J. DiNicolantonio
Ochsner Journal March 2018, 18 (1) 81-87;
Mark F. McCarty
1Catalytic Longevity, Carlsbad, CA
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James H. O'Keefe
2Department of Cardiology, Mid America Heart Institute, Saint Luke's Health System, Kansas City, MO
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James J. DiNicolantonio
2Department of Cardiology, Mid America Heart Institute, Saint Luke's Health System, Kansas City, MO
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Article Information

vol. 18 no. 1 81-87
PubMed 
29559876

Published By 
Ochsner Journal
Print ISSN 
1524-5012
Online ISSN 
1524-5012
History 
  • Published online March 1, 2018.

Copyright & Usage 
© Academic Division of Ochsner Clinic Foundation 2018

Author Information

  1. Mark F. McCarty, BA1,
  2. James H. O'Keefe, MD2 and
  3. James J. DiNicolantonio, PharmD2
  1. 1Catalytic Longevity, Carlsbad, CA
  2. 2Department of Cardiology, Mid America Heart Institute, Saint Luke's Health System, Kansas City, MO
  1. Address correspondence to James J. DiNicolantonio, PharmD, Department of Cardiology, Mid America Heart Institute, Saint Luke's Health System, 4401 Wornall Road 600, Kansas City, MO 64111. Tel: (607) 738-8853. Email: jjdinicol{at}gmail.com
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Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection
Mark F. McCarty, James H. O'Keefe, James J. DiNicolantonio
Ochsner Journal Mar 2018, 18 (1) 81-87;

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Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection
Mark F. McCarty, James H. O'Keefe, James J. DiNicolantonio
Ochsner Journal Mar 2018, 18 (1) 81-87;
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  • Article
    • Abstract
    • INTRODUCTION
    • METHODS
    • DIETARY GLYCINE REGULATION OF GLUTATHIONE SYNTHESIS
    • HEALTH-PROTECTIVE POTENTIAL OF SUPPLEMENTAL GLYCINE
    • GLYCINE AND METABOLIC SYNDROME
    • ANTIINFLAMMATORY EFFECTS OF GLYCINE
    • GLYCINE AND VASCULAR HEALTH
    • IMPACTS ON CANCER, CONNECTIVE TISSUE, AND THE CENTRAL NERVOUS SYSTEM
    • GLYCINE AS A SUPPLEMENTAL NUTRIENT
    • CONCLUSION
    • ACKNOWLEDGMENTS
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

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Keywords

  • Acetylcysteine
  • chloride channels
  • glucagon
  • glucagon-like peptide 1
  • glutathione
  • glutathione synthase
  • glycine

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