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Case ReportCASE REPORTS AND CLINICAL OBSERVATIONS
Open Access

Benign Feminizing Adrenal Tumor in an Adult Male

Raza M. Ahmad, Kyle Ingram and Ralph Corsetti
Ochsner Journal September 2020, 20 (3) 311-314; DOI: https://doi.org/10.31486/toj.19.0031
Raza M. Ahmad
1The University of Queensland Faculty of Medicine, Ochsner Clinical School, New Orleans, LA
MD
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Kyle Ingram
2Department of Surgery, Ochsner Clinic Foundation, New Orleans, LA
MD
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Ralph Corsetti
1The University of Queensland Faculty of Medicine, Ochsner Clinical School, New Orleans, LA
2Department of Surgery, Ochsner Clinic Foundation, New Orleans, LA
MD
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  • For correspondence: rcorsetti@ochsner.org
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Article Figures & Data

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  • Figure 1.
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    Figure 1.

    Computed tomography scan of abdomen and pelvis with contrast shows interval development of a 2.8-cm left adrenal nodule with imaging characteristics consistent with an adenoma (arrow).

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    Figure 2.

    The left adrenal gland and adenoma have benign macroscopic features such as encapsulation and a homogenous appearance.

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    Figure 3.

    Features of the microscopic image (hematoxylin and eosin stain, 50×) of the adrenal adenoma are consistent with a benign appearance: <1 mitotic figure per 50 high power fields, no atypical mitotic figures, no necrosis, clear cells >25%, and a modified Weiss score of 0.

Tables

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    Table 1.

    Pituitary Hormonal Workup

    TestResultReference Range
    Prolactin, ng/mL10.32.0-18.0
    Luteinizing hormone, mIU/mL3.11.5-9.3
    Follicle-stimulating hormone, mIU/mL0.81.6-8.0
    Thyroid-stimulating hormone, mIU/L2.080.4-4.5
    Thyroxine, ng/dL1.30.8-1.8
    Plasma renin, ng/mL/h0.750.6-4.3
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    Table 2.

    Adrenal Intermediaries Workup

    TestResultReference Range
    Androstenedione, ng/dL9640-190
    Dehydroepiandrosterone sulfate, mcg/dL17370-495
    17-ketosteroids, mg/24 h10.75.3-17.6
    Deoxycorticosterone, ng/dL4210-79
    Progesterone, ng/mL<0.5<1.4
    17-hydroxyprogesterone, ng/dL18133-195
    Metanephrines, free, pg/mL40<57
    Metanephrines, total urine, pg/mL8244-261
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    Table 3.

    Hypercortisolism (Cushing Syndrome) Workup

    TestResultReference Range
    Urinary free cortisol, mcg/24 h193.5-45
    Cortisol, 8:00 am, mcg/dL18.810-20
    Adrenocorticotropic hormone, pg/mL126-50
    Dehydroepiandrosterone sulfate, mcg/dL17370-495
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Ochsner Journal: 20 (3)
Ochsner Journal
Vol. 20, Issue 3
Sep 2020
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Benign Feminizing Adrenal Tumor in an Adult Male
Raza M. Ahmad, Kyle Ingram, Ralph Corsetti
Ochsner Journal Sep 2020, 20 (3) 311-314; DOI: 10.31486/toj.19.0031

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Benign Feminizing Adrenal Tumor in an Adult Male
Raza M. Ahmad, Kyle Ingram, Ralph Corsetti
Ochsner Journal Sep 2020, 20 (3) 311-314; DOI: 10.31486/toj.19.0031
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Keywords

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