Case ReportCASE REPORTS AND CLINICAL OBSERVATIONS
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Rare Case of Primary Pulmonary Pleomorphic Liposarcoma Treated With Multimodal Therapy

Treshita Dey, Divya Khosla, Divyesh Kumar, Debajyoti Chatterjee, Renu Madan, Harjeet Singh, Harkant Singh and Rakesh Kapoor
Ochsner Journal December 2021, 21 (4) 431-435; DOI: https://doi.org/10.31486/toj.20.0164

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Figures

  • Figure 1.
    Figure 1.

    (A) Contrast-enhanced computed tomography (CECT) shows pleural-based heterogenous hypodense mass. (B) Baseline positron emission tomography–computed tomography shows local disease. (C) CECT shows large abdominopelvic mass. (D) CECT shows presacral deposit.

  • Figure 2.
    Figure 2.

    (A) Pleomorphic liposarcoma tumor deposit shows admixture of pleomorphic lipoblasts with epithelioid cells (hematoxylin and eosin, ×100). (B) Pleomorphic liposarcoma tumor deposit shows multivacuolated lipoblasts with indented pleomorphic nuclei (hematoxylin and eosin, ×200). (C) Pleomorphic liposarcoma cells are positive for S-100 (immunohistochemistry, ×200). (D) Pleomorphic liposarcoma cells show diffuse p53 expression (immunohistochemistry, ×200).

Tables

  • Table.

    Pleomorphic Liposarcoma Cases Reported in the Literature With Treatment and Outcome Details

    StudyAge, yearsSurgeryRadiotherapyChemotherapyPattern of RecurrenceOutcome
    Krygier et al, 1997949LobectomyYes (40 Gy)YesBone metastasisDied at 8 months
    Ibe et al, 20051136LobectomyNoNoLocalDied at 2 months
    Achir et al, 20091449PneumonectomyNoNoNo recurrenceAlive at 3 years
    Chen et al, 2014349Complete resectionYesYesBone metastasisAlive at ≥16 months
    Our case32Complete resectionYes (30 Gy)YesPeritoneal metastasisAlive at 3 years
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