Evaluation of the Diagnostic Accuracy of the T2Resistance Panel (Research Use Only) in Patients With Possible Bacterial Bloodstream Infections

T2Resistance Panel results compared to simultaneously drawn blood culture results from patients with a possible bloodstream infection.

^aNone detected=no target genes were detected with T2R testing.

^bBlood culture had 3 bacterial species: Enterococcus faecium (vancomycin resistant); Escherichia coli (ampicillin-sulbactam, amoxicillin-clavulanate, cefazolin, cefepime, and ceftriaxone resistant); and methicillin-resistant Staphylococcus epidermidis (MRSE). T2R Panel results were positive for vanA/B and positive for bla_CTX-M-14/15.

^cBlood culture had 3 bacterial species: methicillin-resistant Staphylococcus epidermidis, Staphylococcus haemolyticus (oxacillin susceptible), and Staphylococcus capitis (oxacillin resistant). In the T2R Panel results, a mecA/C gene was not detected.

^dPatients having a negative simultaneous blood culture but a different positive blood culture collected within 48 hours of the original simultaneous blood culture/T2R sample had their original negative simultaneous blood culture tested with the T2R Panel.

BC, blood culture; E cloacae, Enterobacter cloacae; E coli, Escherichia coli; E faecalis, Enterococcus faecalis; E faecium, Enterococcus faecium; h, hour; K pneumoniae, Klebsiella pneumoniae; MRSA, methicillin-resistant Staphylococcus aureus; MRSE, methicillin-resistant Staphylococcus epidermidis; MSSA, methicillin-susceptible Staphylococcus aureus; MSSE, methicillin-susceptible Staphylococcus epidermidis; neg, negative; P aeruginosa, Pseudomonas aeruginosa; P mirabilis, Proteus mirabilis; P shigelloides, Plesiomonas shigelloides; R ornithinolytica, Raoultella ornithinolytica; S aureus, Staphylococcus aureus; S capitis, Staphylococcus capitis; S cohnii, Staphylococcus cohnii; S haemolyticus; Staphylococcus haemolyticus; T2R, T2Resistance Panel.