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Research ArticleUnder the Microscope

Utility of Heart Biopsy in Transplant Patients

Edwin N. Beckman, Mandeep R. Mehra, Myung H. Park and Robert L. Scott
Ochsner Journal October 2001, 3 (4) 219-222;
Edwin N. Beckman
Department of Pathology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA
MD
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Mandeep R. Mehra
Department of Pathology, and Cardiomyopathy and Heart Transplantation Center, Department of Cardiology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA
MD
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Myung H. Park
Department of Pathology, and Cardiomyopathy and Heart Transplantation Center, Department of Cardiology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA
MD
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Robert L. Scott
Department of Pathology, and Cardiomyopathy and Heart Transplantation Center, Department of Cardiology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA
MD
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Article Figures & Data

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  • Figure 1.
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    Figure 1.

    Grade 1A changes. Perivascular lymphocytic collections. Hematoxylin and eosin

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    Figure 2.

    Interstitial lymphocytic infiltrate with obscured myocytes. This region is interpreted as having two adjacent foci, and it therefore graded as Grade 3A. If there were only a single focus in all the biopsy specimens, the picture would be Grade 2. Hematoxylin and eosin. 100X

  • Figure 3.
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    Figure 3.

    Grade 3B. Global lymphocytic infiltrate between myocytes. Hematoxylin and eosin. 100X

  • Figure 4.
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    Figure 4.

    Humoral rejection. Positive immunofluorescence for compliment (C-3) along intima of vessel; this specimen was also had vascular positivity for IgM. Immunofluorescence stain. 400X

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    Figure 5.

    Toxoplasmosis. Cyst of toxoplasmosis within a myocyte. Hematoxylin and eosin. 400X

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    Figure 6.

    Amyloidosis. Amorphous pink deposits around vessels and within the interstitium. Hematoxylin and eosin. 250X

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    Dr. Beckman has been a pathologist at the Ochsner Clinic and Ochsner Foundation Hospital for 25 years, performing general anatomic pathology but specializing in cardiovascular and genitourinary pathology. He is Clinical Associate Professor in Pathology at Tulane Medical School

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Ochsner Journal
Vol. 3, Issue 4
Oct 2001
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Utility of Heart Biopsy in Transplant Patients
Edwin N. Beckman, Mandeep R. Mehra, Myung H. Park, Robert L. Scott
Ochsner Journal Oct 2001, 3 (4) 219-222;

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Utility of Heart Biopsy in Transplant Patients
Edwin N. Beckman, Mandeep R. Mehra, Myung H. Park, Robert L. Scott
Ochsner Journal Oct 2001, 3 (4) 219-222;
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