Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
  • About Us
    • About the Ochsner Journal
    • Editorial Board
  • More
    • Alerts
    • Feedback
  • Other Publications
    • Ochsner Journal Blog

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Ochsner Journal
  • Other Publications
    • Ochsner Journal Blog
  • My alerts
  • Log in
Ochsner Journal

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
  • About Us
    • About the Ochsner Journal
    • Editorial Board
  • More
    • Alerts
    • Feedback
Research ArticleFeatured Articles

Nonalcoholic Fatty Liver Disease from the Perspective of an Internist

Satheesh Nair
Ochsner Journal March 2002, 4 (2) 92-97;
Satheesh Nair
Section on Gastroenterology, Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, LA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. ↵
    1. Ludwig J.,
    2. Viggiano T. R.,
    3. McGill D. B.
    (1980) Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 55:434–438, pmid:7382552.
    OpenUrlCrossRefPubMedWeb of Science
  2. ↵
    1. Day C. P.,
    2. James O. F.
    (1998) Steatohepatitis: a tale of two “hits”? Gastroenterology 114:842–845, pmid:9547102.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Reid A. E.
    (2001) Nonalcoholic steatohepatitis. Gastroenterology 121:710–723, pmid:11522755.
    OpenUrlCrossRefPubMedWeb of Science
  4. ↵
    1. Weltman M. D.,
    2. Farrell G. C.,
    3. Liddle C.
    (1996) Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 111:1645–1653, pmid:8942745.
    OpenUrlCrossRefPubMedWeb of Science
  5. ↵
    1. Weltman M. D.,
    2. Farrell G. C.,
    3. Hall P.
    (1998) Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. Hepatology 27:128–133, pmid:9425928.
    OpenUrlCrossRefPubMedWeb of Science
    1. Wigg A. J.,
    2. Roberts-Thomson I. C.,
    3. Dymock R. B.
    (2001) The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut 48:206–211, pmid:11156641.
    OpenUrlAbstract/FREE Full Text
    1. Berson A.,
    2. DeBeco V.,
    3. Letteron P.
    (1998) Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes. Gastroenterology 114:764–774, pmid:9516397.
    OpenUrlCrossRefPubMedWeb of Science
    1. Nair S.,
    2. Cope K.,
    3. Risby T. H.
    (2001) Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis. Am J Gastroenterol 96:1200–1204, pmid:11316170.
    OpenUrlCrossRefPubMedWeb of Science
  6. ↵
    1. Powell E. E.,
    2. Cooksley W. G.,
    3. Hanson R.
    (1990) The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology 11:74–80, pmid:2295475.
    OpenUrlCrossRefPubMedWeb of Science
  7. ↵
    1. Clark J. M.,
    2. Brancati F.,
    3. Diehl A. M.
    (2001) Non alcoholic fatty liver disease: the most common cause of abnormal liver enzymes in the US population. Gastroenterology 120:A65.
    OpenUrl
  8. ↵
    1. Wanless I. R.,
    2. Lentz J. S.
    (1990) Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. Hepatology 12:1106–1110, pmid:2227807.
    OpenUrlCrossRefPubMedWeb of Science
  9. ↵
    1. Bellentani S.,
    2. Saccoccio G.,
    3. Masutti F.
    (2000) Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med 132:112–117, pmid:10644271.
    OpenUrlPubMedWeb of Science
  10. ↵
    1. Poonawala A.,
    2. Nair S.,
    3. Thuluvath P. J.
    (2000) Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study. Hepatology 32:689–692, pmid:11003611, (4 Pt 1).
    OpenUrlCrossRefPubMedWeb of Science
  11. ↵
    1. Caldwell S. H.,
    2. Oelsner D. H.,
    3. Iezzoni J. C.,
    4. Hespenheide E. E.,
    5. Battle E. H.,
    6. Driscoll C. J.
    (1999) Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 29:664–669, pmid:10051466.
    OpenUrlCrossRefPubMedWeb of Science
  12. ↵
    1. Charlton M.,
    2. Kasparova P.,
    3. Weston S.
    (2001) Frequency of non-alcoholic steatohepatitis as a cause of advanced liver disease. Liver Transpl 7:608–614, pmid:11460228.
    OpenUrlCrossRefPubMedWeb of Science
  13. ↵
    1. Matteoni C. A.,
    2. Younossi Z. M.,
    3. Gramlich T.
    (1999) Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 116:1413–1419, pmid:10348825.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    1. Dixon J. B.,
    2. Bhathal P. S.,
    3. O'Brien P. E.
    (2001) Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. Gastroenterology 121:91–100, pmid:11438497.
    OpenUrlCrossRefPubMedWeb of Science
  15. ↵
    1. Nair S.,
    2. Eason J. D.,
    3. Loss G. E.
    (2001) Relative Risk of Hepatocellular Carcinoma in Cirrhosis due to Fatty Liver Disease: A Study Based on Incidental Hepatocellular Carcinoma in Liver Transplant Recipient. Hepatology 34:462A.
    OpenUrl
  16. ↵
    1. Murata Y.,
    2. Ogawa Y.,
    3. Saibara T.
    (2000) Unrecognized hepatic steatosis and non-alcoholic steatohepatitis in adjuvant tamoxifen for breast cancer patients. Oncol Rep 7:1299–1304, pmid:11032933.
    OpenUrlPubMed
  17. ↵
    1. Lin H. Z.,
    2. Yang S. Q.,
    3. Chuckaree C.
    (2000) Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med 6:998–1003, pmid:10973319.
    OpenUrlCrossRefPubMedWeb of Science
  18. ↵
    1. Marchesini G.,
    2. Brizi M.,
    3. Bianchi G.
    (2001) Metformin in non-alcoholic steatohepatitis. Lancet 358:893–894, pmid:11567710.
    OpenUrlCrossRefPubMedWeb of Science
  19. ↵
    1. Caldwell S. H.,
    2. Hespenheide E. E.,
    3. Redick J. A.
    (2001) A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol 96:519–525, pmid:11232700.
    OpenUrlCrossRefPubMedWeb of Science
  20. ↵
    1. Abdelmalek M. F.,
    2. Angulo P.,
    3. Jorgensen R. A.
    (2001) Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 96:2711–2717, pmid:11569700.
    OpenUrlCrossRefPubMedWeb of Science
  21. ↵
    1. Laurin J.,
    2. Lindor K. D.,
    3. Crippin J. S.
    (1996) Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study. Hepatology 23:1464–1467, pmid:8675165.
    OpenUrlCrossRefPubMedWeb of Science
  22. ↵
    1. Hasegawa T.,
    2. Yoneda M.,
    3. Nakamura K.
    (2001) Plasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. Aliment Pharmacol Ther 15:1667–1672, pmid:11564008.
    OpenUrlCrossRefPubMedWeb of Science
  23. ↵
    1. Lavine J. E.
    (2000) Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study. J Pediatr 136:734–738, pmid:10839868.
    OpenUrlCrossRefPubMedWeb of Science
  24. ↵
    1. Contos M. J.,
    2. Cales W.,
    3. Sterling R. K.
    (2001) Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis. Liver Transpl 7:363–373, pmid:11303298.
    OpenUrlCrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

Ochsner Journal
Vol. 4, Issue 2
Mar 2002
  • Table of Contents
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Ochsner Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Nonalcoholic Fatty Liver Disease from the Perspective of an Internist
(Your Name) has sent you a message from Ochsner Journal
(Your Name) thought you would like to see the Ochsner Journal web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Nonalcoholic Fatty Liver Disease from the Perspective of an Internist
Satheesh Nair
Ochsner Journal Mar 2002, 4 (2) 92-97;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Nonalcoholic Fatty Liver Disease from the Perspective of an Internist
Satheesh Nair
Ochsner Journal Mar 2002, 4 (2) 92-97;
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Pathogenesis
    • Prevalence
    • When to Suspect NAFLD
    • Proceeding With a Typical Evaluation
    • How Serious Is NAFLD?
    • Commonly Used Drugs and NAFLD
    • Treating NAFLD
    • Liver Transplantation
    • Conclusion
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Influence of Preoperative Risk Factors on Outcome After Carotid Endarterectomy
  • Extracranial-Intracranial Bypass in Cerebral Ischemia
  • Vascular Dementia
Show more Featured Articles

Similar Articles

Current Post at the Blog

Elsevier Editors Resign Over Open-Access Fees

Our Content

  • Home
  • Current Issue
  • Ahead of Print
  • Archive
  • Featured Contributors
  • Ochsner Journal Blog
  • Archive at PubMed Central

Information & Forms

  • Instructions for Authors
  • Instructions for Reviewers
  • Submission Checklist
  • FAQ
  • License for Publishing-Author Attestation
  • Patient Consent Form
  • Submit a Manuscript

Services & Contacts

  • Permissions
  • Sign up for our electronic table of contents
  • Feedback Form
  • Contact Us

About Us

  • Editorial Board
  • About the Ochsner Journal
  • Ochsner Health
  • University of Queensland-Ochsner Clinical School
  • Alliance of Independent Academic Medical Centers

© 2023 Ochsner Clinic Foundation

Powered by HighWire