Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
  • About Us
    • About the Ochsner Journal
    • Editorial Board
  • More
    • Alerts
    • Feedback
  • Other Publications
    • Ochsner Journal Blog

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Ochsner Journal
  • Other Publications
    • Ochsner Journal Blog
  • My alerts
  • Log in
Ochsner Journal

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Archive
  • Info for
    • Authors
    • Reviewers
  • About Us
    • About the Ochsner Journal
    • Editorial Board
  • More
    • Alerts
    • Feedback
Research ArticleUnder the Microscope

Alcohol and Liver Disease

Om Prakash and Steve Nelson
Ochsner Journal September 2002, 4 (4) 241-244;
Om Prakash
Molecular Oncology Laboratory, Ochsner Clinic Foundation, New Orleans, LA
PhD
Roles: Head
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Steve Nelson
Alcohol Research Center, Louisiana State University Health Sciences Center, New Orleans, LA
MD
Roles: Director
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

REFERENCES

  1. ↵
    1. Stinson F. S.,
    2. Yi Y-H.,
    3. Grant B. F.
    (1997) Drinking in the U.S.: Main findings from the National Longitudinal Alcohol Epidemiologic Survey, ((6)), In: U.S. Alcohol Epidemiologic Data References Manual NIH Publication no. 99-3519. 1st ed. Washington, DC: U.S. Government Printing Office.
  2. ↵
    1. McGinnis J. M.,
    2. Foege W. H.
    (1993) Actual causes of death in the United States. JAMA 270:2207–2212, pmid:8411605.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Angell M.,
    2. Kassirer J. P.
    (1994) Alcohol and other drugs – toward a more rational and consistent policy. N Engl J Med 331:537–539, pmid:8041422.
    OpenUrlCrossRefPubMedWeb of Science
  4. ↵
    1. Saadatmand F.,
    2. Stinson F. S.,
    3. Grant B. F.
    (2000) Surveillance Report #54: Liver Cirrhosis Mortality in the United States 1970–97. National Institute on Alcohol Abuse and Alcoholism, Division of Biometry and Epidemiology. Alcohol Epidemiologic Data System, Bethesda, MD.
  5. ↵
    1. Morgan M. Y.,
    2. Sherlock S.
    (1977) Sex-related differences among 100 patients with alcoholic liver disease. Br Med J 1:939–941, pmid:851792.
    OpenUrlAbstract/FREE Full Text
  6. ↵
    1. Nakamura S.,
    2. Takezawa Y.,
    3. Sato T.
    (1979) Alcoholic liver disease in women. Tohoku J Exp Med 129:351–355, pmid:524359.
    OpenUrlPubMed
  7. ↵
    1. Pequignot G.,
    2. Tuyns A. J.,
    3. Berta J. L.
    (1978) Ascitic cirrhosis in relation to alcohol consumption. Int J Epidemiol 7:113–120, pmid:681057.
    OpenUrlCrossRefPubMedWeb of Science
  8. ↵
    (2000) Congress on alcohol and health: Highlights from current research from the Secretary of Health and Human Services, 429–30, 10th special report to U.S, U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health. National Institute on Alcohol Abuse and Alcoholism, NIH publication no. 00-1583.
  9. ↵
    1. Becker U.,
    2. Deis A.,
    3. Sorensen T. I.
    (1996) Prediction of risk of liver disease by alcohol intake, sex, and age: a prospective population study. Hepatology 23:1025–1029, pmid:8621128.
    OpenUrlCrossRefPubMedWeb of Science
  10. ↵
    1. Frezza M.,
    2. di Padova C.,
    3. Pozzato G.
    (1990) High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. N Engl J Med 322:95–99, pmid:2248624.
    OpenUrlCrossRefPubMedWeb of Science
  11. ↵
    1. Seitz H. K.,
    2. Egerer G.,
    3. Simanowski U. A.
    (1993) Human gastric alcohol dehydrogenase activity: effect of age, sex, and alcoholism. Gut 34:1433–1437, pmid:8244116.
    OpenUrlAbstract/FREE Full Text
  12. ↵
    1. Bosron W. F.,
    2. Li T. K.
    (1986) Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 6:502–510, pmid:3519419.
    OpenUrlCrossRefPubMedWeb of Science
  13. ↵
    1. Chao Y. C.,
    2. Liou S. R.,
    3. Chung Y. Y.
    (1994) Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients. Hepatology 19:360–366, pmid:7904979.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    1. Shibuya A.,
    2. Yoshida A.
    (1988) Genotypes of alcohol-metabolizing enzymes in Japanese with alcohol liver diseases: a strong association of the usual Caucasian-type aldehyde dehydrogenase gene (ALDH1(2)) with the disease. Am J Hum Genet 43:744–748, pmid:3189338.
    OpenUrlPubMedWeb of Science
  15. ↵
    1. Lieber C. S.
    (1994) Alcohol and the liver: 1994 update. Gastroenterology 106:1085–1105, pmid:8143977.
    OpenUrlCrossRefPubMedWeb of Science
  16. ↵
    1. Friedman S. L.
    (1999) Stellate cell activation in alcoholic fibrosis—an overview. Alcohol Clin Exp Res 23:904–910, pmid:10371412.
    OpenUrlCrossRefPubMedWeb of Science
  17. ↵
    1. Niemela O.,
    2. Juvonen T.,
    3. Parkkila S.
    (1991) Immunohistochemical demonstration of acetaldehyde-modified epitopes in human liver after alcohol consumption. J Clin Invest 87:1367–1374, pmid:1707062.
    OpenUrlPubMedWeb of Science
  18. ↵
    1. Holstege A.,
    2. Bedossa P.,
    3. Poynard T.
    (1994) Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: localization and association with progression of liver fibrosis. Hepatology 19:367–374, pmid:7507463.
    OpenUrlCrossRefPubMedWeb of Science
  19. ↵
    1. Ronis M. J.,
    2. Huang J.,
    3. Crouch J.
    (1993) Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats. J Pharmacol Exp Ther 264:944–950, pmid:8437134.
    OpenUrlAbstract/FREE Full Text
  20. ↵
    1. Prakash O.,
    2. Mason A.,
    3. Luftig R. B.
    (2002) Hepatitis C virus (HCV) and human immunodeficiency virus type 1 (hiv-1) infections in alcoholics. Front Biosci 7:e286–300, pmid:12086918.
    OpenUrlPubMed
  21. ↵
    1. Koop D. R.,
    2. Klopfenstein B.,
    3. Iimuro Y.
    (1997) Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1. Mol Pharmacol 51:944–950, pmid:9187260.
    OpenUrlAbstract/FREE Full Text
  22. ↵
    1. Lieber C. S.
    (2000) Alcoholic liver disease: new insights in pathogenesis lead to new treatments. J Hepatol 32((1 Suppl)):113–128, pmid:10728799.
    OpenUrlPubMedWeb of Science
  23. ↵
    1. Bautista A. P.
    (2001) Free radicals, chemokines, and cell injury in HIV-1 and SIV infections and alcoholic hepatitis. Free Radic Biol Med 31:1527–1532, pmid:11744325.
    OpenUrlCrossRefPubMedWeb of Science
  24. ↵
    1. Kono H.,
    2. Rusyn I.,
    3. Yin M.
    (2000) NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest 106:867–872, pmid:11018074.
    OpenUrlCrossRefPubMedWeb of Science
  25. ↵
    1. Fraser A.,
    2. Evan G. A.
    (1996) A license to kill. Cell 85:781–784, pmid:8681372.
    OpenUrlCrossRefPubMedWeb of Science
  26. ↵
    1. Tewari M.,
    2. Dixit V. M.
    (1996) Recent advances in tumor necrosis factor and CD40 signaling. Curr Opin Genet Dev 6:39–44, pmid:8791485.
    OpenUrlCrossRefPubMedWeb of Science
  27. ↵
    1. Yin M.,
    2. Wheeler M. D.,
    3. Kono H.
    (1999) Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology 117:942–952, pmid:10500078.
    OpenUrlCrossRefPubMedWeb of Science
  28. ↵
    1. Naveau S.,
    2. Abella A.,
    3. Raynard B.
    (2001) Tumor necrosis factor soluble receptor p55 and lipid peroxidation in patients with acute alcoholic hepatitis. Am J Gastroenterol 96:3361–3367, pmid:11774950.
    OpenUrlCrossRefPubMedWeb of Science
  29. ↵
    1. Thornton A. J.,
    2. Strieter R. M.,
    3. Lindley I.
    (1990) Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J Immunol 144:2609–2613, pmid:2156928.
    OpenUrlAbstract
  30. ↵
    1. Ohkubo K.,
    2. Masumoto T.,
    3. Horiike N.
    (1998) Induction of CINC (interleukin-8) production in rat liver by non-parenchymal cells. J Gastroenterol Hepatol 13:696–702, pmid:9715420.
    OpenUrlPubMedWeb of Science
  31. ↵
    1. Hong F.,
    2. Kim W. H.,
    3. Tian Z.
    (2002) Elevated interleukin-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol-induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-x(L) proteins. Oncogene 21:32–43, pmid:11791174.
    OpenUrlCrossRefPubMedWeb of Science
  32. ↵
    1. Annoni G.,
    2. Weiner F. R.,
    3. Zern M. A.
    (1992) Increased transforming growth factor-beta 1 gene expression in human liver disease. J Hepatol 14:259–264, pmid:1380023.
    OpenUrlCrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

Ochsner Journal
Vol. 4, Issue 4
Sep 2002
  • Table of Contents
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Ochsner Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Alcohol and Liver Disease
(Your Name) has sent you a message from Ochsner Journal
(Your Name) thought you would like to see the Ochsner Journal web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Alcohol and Liver Disease
Om Prakash, Steve Nelson
Ochsner Journal Sep 2002, 4 (4) 241-244;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Alcohol and Liver Disease
Om Prakash, Steve Nelson
Ochsner Journal Sep 2002, 4 (4) 241-244;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • GENDER
    • ETHNICITY
    • ALCOHOL METABOLISM AND LIVER INJURY
    • SUMMARY AND CONCLUSIONS
    • REFERENCES
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Isolation of Endothelial Cells and Vascular Smooth Muscle Cells from Internal Mammary Artery Tissue
  • Chicken Sarcoma to Human Cancers: A Lesson in Molecular Therapeutics
  • Inhibition of Erythroleukemia Cell Growth by Triplex-forming RNAs
Show more Under The Microscope

Similar Articles

Ochsner Journal Blog

Current Post

Be Careful Where You Publish

Our Content

  • Home
  • Current Issue
  • Ahead of Print
  • Archive
  • Featured Contributors
  • Ochsner Journal Blog
  • Archive at PubMed Central

Information & Forms

  • Instructions for Authors
  • Instructions for Reviewers
  • Submission Checklist
  • FAQ
  • License for Publishing-Author Attestation
  • Patient Consent Form
  • Submit a Manuscript

Services & Contacts

  • Permissions
  • Sign up for our electronic table of contents
  • Feedback Form
  • Contact Us

About Us

  • Editorial Board
  • About the Ochsner Journal
  • Ochsner Health
  • University of Queensland-Ochsner Clinical School
  • Alliance of Independent Academic Medical Centers

© 2025 Ochsner Clinic Foundation

Powered by HighWire