RT Journal Article
SR Electronic
T1 Diffuse Pontine Astrocytoma With Lipocytic Differentiation
JF Ochsner Journal
JO Ochsner J
FD O. P. Jindal Global University
SP 244
OP 248
VO 12
IS 3
A1 Randall Craver
A1 Christopher Arcement
A1 Tammuella Chrisentery Singleton
YR 2012
UL http://www.ochsnerjournal.org/content/12/3/244.abstract
AB A 7-year-old boy was treated with radiation and chemotherapy for a diffuse pontine glioma. At autopsy, 8 months after diagnosis, the tumor was a diffuse grade II fibrillary astrocytoma with prominent lipocytic differentiation. Literature review suggests that lipocytic differentiation in low-grade astrocytomas occurs in a variety of patient ages, anatomic sites, grades, and astrocytic subtypes. Although the majority of low-grade lipoastrocytomas have behaved benignly, this child's lipoastrocytoma was the underlying cause of death. This outcome suggests that the outcomes of low-grade lipoastrocytic tumors may be expected to be the same as the underlying tumor subtype.