RT Journal Article
SR Electronic
T1 Dexmedetomidine for Anterior Mediastinal Mass Computed Tomography-Guided Biopsy: A Case Series
JF Ochsner Journal
JO Ochsner J
FD O. P. Jindal Global University
SP 541
OP 543
VO 13
IS 4
A1 Dominic S. Carollo
A1 Sophie Pestieau
A1 Richard Bosco
YR 2013
UL http://www.ochsnerjournal.org/content/13/4/541.abstract
AB Background Sedation of children undergoing biopsies of anterior mediastinal masses can be challenging because of the absolute necessity of ensuring minimal smooth muscle relaxation and preventing airway collapse. Furthermore, positive pressure ventilation may be difficult or impossible and may also pose the additional risks of hemodynamic compromise in the pediatric patient.Case Reports We present a case series of 3 children who were successfully sedated for computed tomography (CT)-guided mediastinal biopsies with dexmedetomidine.Conclusion Dexmedetomidine, a selective alpha-2 adrenoreceptor agonist that maintains the smooth musculature of the pediatric airway, provides the ability to sustain spontaneous ventilation in patients with airway compression. Dexmedetomidine is a safe, reliable anesthetic for biopsy of children with anterior mediastinal masses.