RT Journal Article SR Electronic T1 Two Cases of Fulminant Hepatic Failure from Amanita phalloides Poisoning Treated Additively by Homeopathy JF Ochsner Journal JO Ochsner J FD O. P. Jindal Global University SP 252 OP 258 VO 14 IS 2 A1 Frass, Michael A1 Zagorchev, Petko A1 Yurukova, Vasilka A1 Wulkersdorfer, Beatrix A1 Thieves, Karin A1 Zedtwitz-Liebenstein, Konstantin A1 Bursch, Willfried A1 Kaye, Alan David YR 2014 UL http://www.ochsnerjournal.org/content/14/2/252.abstract AB Background Intoxication with Amanita phalloides is associated with high morbidity and mortality. Treatment therapies include general support, toxin elimination, pharmacotherapy with agents such as the hepatoprotective agent silibinin, and, in extreme states, liver transplantation. Despite these therapeutic interventions, mortality remains relatively high.Case Reports We present reports of 2 patients with severe hepatic failure following intoxication with Amanita phalloides. Both patients were admitted to the intensive care unit; 1 patient suffered from hepatic failure solely, and the second patient experienced severe 5-organ failure. In addition to conventional intensive care treatment, both patients were treated additively with classical homeopathy. The 2 patients survived without any residual pathological sequelae.Conclusion Based on the 2 cases, including 1 extreme situation, we suggest that adjunctive homeopathic treatment has a role in the treatment of acute Amanita phalloides–induced toxicity following mushroom poisoning. Additional studies may clarify a more precise dosing regimen, standardization, and better acceptance of homeopathic medicine in the intensive care setting.