TY - JOUR T1 - Two Cases of Fulminant Hepatic Failure from <em>Amanita phalloides</em> Poisoning Treated Additively by Homeopathy JF - Ochsner Journal JO - Ochsner J SP - 252 LP - 258 VL - 14 IS - 2 AU - Michael Frass AU - Petko Zagorchev AU - Vasilka Yurukova AU - Beatrix Wulkersdorfer AU - Karin Thieves AU - Konstantin Zedtwitz-Liebenstein AU - Willfried Bursch AU - Alan David Kaye Y1 - 2014/06/20 UR - http://www.ochsnerjournal.org/content/14/2/252.abstract N2 - Background Intoxication with Amanita phalloides is associated with high morbidity and mortality. Treatment therapies include general support, toxin elimination, pharmacotherapy with agents such as the hepatoprotective agent silibinin, and, in extreme states, liver transplantation. Despite these therapeutic interventions, mortality remains relatively high.Case Reports We present reports of 2 patients with severe hepatic failure following intoxication with Amanita phalloides. Both patients were admitted to the intensive care unit; 1 patient suffered from hepatic failure solely, and the second patient experienced severe 5-organ failure. In addition to conventional intensive care treatment, both patients were treated additively with classical homeopathy. The 2 patients survived without any residual pathological sequelae.Conclusion Based on the 2 cases, including 1 extreme situation, we suggest that adjunctive homeopathic treatment has a role in the treatment of acute Amanita phalloides–induced toxicity following mushroom poisoning. Additional studies may clarify a more precise dosing regimen, standardization, and better acceptance of homeopathic medicine in the intensive care setting. ER -