PT - JOURNAL ARTICLE AU - Kyaw, Htoo AU - Shaikh, Atif Z. AU - Yaratha, Gokul AU - Deepika, Misra TI - Septic Embolic Stroke Resulting From <em><span class="named-content genus-species" id="named-content-1">Staphylococcus lugdunensis</span></em> Endocarditis DP - 2017 Jun 20 TA - Ochsner Journal PG - 184--188 VI - 17 IP - 2 4099 - http://www.ochsnerjournal.org/content/17/2/184.short 4100 - http://www.ochsnerjournal.org/content/17/2/184.full SO - Ochsner J2017 Jun 20; 17 AB - Background: Staphylococcus lugdunensis, a member of the coagulase-negative staphylococci (CoNS), has been recognized as a causal organism for infective endocarditis since the 1980s. Although most CoNS have an insidious and chronic nature, they are involved in a variety of systemic infections. S lugdunensis infective endocarditis is a rare entity but is as catastrophic as Staphylococcus aureus infective endocarditis and requires aggressive antibiotic therapy and, typically, valve replacement. S lugdunensis infective endocarditis–induced septic embolic cerebrovascular accident has rarely been reported in the literature.Case Report: We present the case of a 63-year-old African American man who presented with sudden-onset aphasia and right-sided hemiplegia and was admitted for the management of cerebrovascular accident. Afterwards, he developed a fever and was found to have S lugdunensis bacteremia, with subsequent imaging revealing vegetations of the mitral valve. Despite being treated with culture-appropriate antibiotics, he remained persistently bacteremic and required surgical mitral valve replacement.Conclusion: S lugdunensis infective endocarditis is rare but can have a malignant course and requires early surgical intervention in most cases.