PT - JOURNAL ARTICLE AU - Babak K. Kashy AU - Alaa A. Abd-Elsayed AU - Ehab Farag AU - Maria Yared AU - Roya Vakili AU - Wael Ali Sakr Esa TI - Amputation as an Unusual Treatment for Therapy-Resistant Complex Regional Pain Syndrome, Type 1 AID - 10.1043/TOJ-14-0074 DP - 2015 Dec 21 TA - Ochsner Journal PG - 441--442 VI - 15 IP - 4 4099 - http://www.ochsnerjournal.org/content/15/4/441.short 4100 - http://www.ochsnerjournal.org/content/15/4/441.full SO - Ochsner J2015 Dec 21; 15 AB - Background Complex regional pain syndrome, type 1 (CRPS-1) causes severe pain that can be resistant to multiple treatment modalities. Amputation as a form of long-term treatment for therapy-resistant CRPS-1 is controversial.Case Report We report the case of a 38-year-old man who failed all treatment modalities for CRPS-1, including medication, steroid injections, and spinal cord stimulator implantation. Below-the-knee amputation to relieve intractable foot and ankle pain resulted in a favorable outcome for this patient.Conclusion Select patients with severe CRPS-1 who are unresponsive to all forms of treatment for pain may benefit from amputation as a last option for relief of suffering. Larger studies are needed to prove the efficacy of amputation.