PT  - JOURNAL ARTICLE
AU  - Ahmad, Raza M.
AU  - Ingram, Kyle
AU  - Corsetti, Ralph
TI  - Benign Feminizing Adrenal Tumor in an Adult Male
AID  - 10.31486/toj.19.0031
DP  - 2020 Sep 21
TA  - Ochsner Journal
PG  - 311--314
VI  - 20
IP  - 3
4099  - http://www.ochsnerjournal.org/content/20/3/311.short
4100  - http://www.ochsnerjournal.org/content/20/3/311.full
SO  - Ochsner J2020 Sep 21; 20
AB  - Background: Feminizing adrenal tumors are rare and generally malignant tumors usually seen in male adults and children. We report the case of a benign feminizing adrenal tumor in a male patient. To our knowledge, only 2 other cases of benign, estrogen-only–secreting adrenal tumors have been reported.Case Report: A 44-year-old male with a history of hypertension presented to his primary care physician with chest tenderness, fatigue, and erectile dysfunction. Hormonal workup and imaging identified an estrogen-only–secreting adrenal adenoma. The adenoma was removed via laparoscopic adrenalectomy, and the patient had a normal postoperative course. Pathologic findings were an adrenal cortical adenoma with a Weiss score of 0 and a Ki-67 score of 0%. At 6-month follow-up, the patient's symptoms had significantly improved, and his previously abnormal sex hormone levels were within normal limits.Conclusion: Given the ambiguity in distinguishing between malignant and benign feminizing adrenal tumors, we suggest that radiologic (via Hounsfield units), clinical (via trending hormone levels), and histopathologic (via Weiss and Ki-67 scores) findings are sufficient to confirm the benign nature of this commonly malignant tumor.