RT Journal Article
SR Electronic
T1 Benign Feminizing Adrenal Tumor in an Adult Male
JF Ochsner Journal
JO Ochsner J
FD O. P. Jindal Global University
SP 311
OP 314
DO 10.31486/toj.19.0031
VO 20
IS 3
A1 Raza M. Ahmad
A1 Kyle Ingram
A1 Ralph Corsetti
YR 2020
UL http://www.ochsnerjournal.org/content/20/3/311.abstract
AB Background: Feminizing adrenal tumors are rare and generally malignant tumors usually seen in male adults and children. We report the case of a benign feminizing adrenal tumor in a male patient. To our knowledge, only 2 other cases of benign, estrogen-only–secreting adrenal tumors have been reported.Case Report: A 44-year-old male with a history of hypertension presented to his primary care physician with chest tenderness, fatigue, and erectile dysfunction. Hormonal workup and imaging identified an estrogen-only–secreting adrenal adenoma. The adenoma was removed via laparoscopic adrenalectomy, and the patient had a normal postoperative course. Pathologic findings were an adrenal cortical adenoma with a Weiss score of 0 and a Ki-67 score of 0%. At 6-month follow-up, the patient's symptoms had significantly improved, and his previously abnormal sex hormone levels were within normal limits.Conclusion: Given the ambiguity in distinguishing between malignant and benign feminizing adrenal tumors, we suggest that radiologic (via Hounsfield units), clinical (via trending hormone levels), and histopathologic (via Weiss and Ki-67 scores) findings are sufficient to confirm the benign nature of this commonly malignant tumor.