RT Journal Article SR Electronic T1 Acrometastasis in Breast Carcinoma JF Ochsner Journal JO Ochsner J FD O. P. Jindal Global University DO 10.31486/toj.22.0105 A1 Galliano, Caroline A1 Bragg, R. Taylor A1 Rangani, Paresh A1 Froom, Mark YR 2023 UL http://www.ochsnerjournal.org/content/early/2023/01/27/toj.22.0105.abstract AB Background: Metastasis to the bone in breast cancer patients is common, but metastasis specifically to the appendicular skeleton is rare. A limited number of cases in the literature describe metastatic breast cancer to the distal limbs, also known as acrometastasis. Acrometastasis in a patient with breast cancer should prompt evaluation for diffuse metastatic disease.Case Report: We describe the case of a patient with recurrent triple-negative metastatic breast cancer who presented with thumb pain and swelling. Radiograph of the hand demonstrated focal soft tissue swelling over the first distal phalanx with erosive changes to the bone. Palliative radiation to the thumb resulted in symptom improvement. However, the patient succumbed to widespread metastatic disease. At autopsy, the thumb lesion was confirmed as metastatic breast adenocarcinoma.Conclusion: Metastatic breast carcinoma to the distal appendicular skeleton, specifically to the first digit, is a rare presentation of bony metastasis and can be an indication of late, widespread disease.